Shannon HE - Search Results

1

Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease.

Bodick NC, Offen WW, Levey AI, Cutler NR, Gauthier SG, Satlin A, Shannon HE, Tollefson GD, Rasmussen K, Bymaster FP, Hurley DJ, Potter WZ, Paul SM. Bodick NC, et al. Among authors: shannon he. Arch Neurol. 1997 Apr;54(4):465-73. doi: 10.1001/archneur.1997.00550160091022. Arch Neurol. 1997. PMID: 9109749 Clinical Trial.

2

The selective muscarinic agonist xanomeline improves both the cognitive deficits and behavioral symptoms of Alzheimer disease.

Bodick NC, Offen WW, Shannon HE, Satterwhite J, Lucas R, van Lier R, Paul SM. Bodick NC, et al. Among authors: shannon he. Alzheimer Dis Assoc Disord. 1997;11 Suppl 4:S16-22. Alzheimer Dis Assoc Disord. 1997. PMID: 9339268 Clinical Trial.

3

Xanomeline, an M(1)/M(4) preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice.

Shannon HE, Rasmussen K, Bymaster FP, Hart JC, Peters SC, Swedberg MD, Jeppesen L, Sheardown MJ, Sauerberg P, Fink-Jensen A. Shannon HE, et al. Schizophr Res. 2000 May 5;42(3):249-59. doi: 10.1016/s0920-9964(99)00138-3. Schizophr Res. 2000. PMID: 10785583

4

The muscarinic M1 agonist xanomeline increases soluble amyloid precursor protein release from Chinese hamster ovary-m1 cells.

Eckols K, Bymaster FP, Mitch CH, Shannon HE, Ward JS, DeLapp NW. Eckols K, et al. Among authors: shannon he. Life Sci. 1995;57(12):1183-90. doi: 10.1016/0024-3205(95)02064-p. Life Sci. 1995. PMID: 7674807

5

Effects of the M1 agonist xanomeline on processing of human beta-amyloid precursor protein (FAD, Swedish mutant) transfected into Chinese hamster ovary-m1 cells.

DeLapp N, Wu S, Belagaje R, Johnstone E, Little S, Shannon H, Bymaster F, Calligaro D, Mitch C, Whitesitt C, Ward J, Sheardown M, Fink-Jensen A, Jeppesen L, Thomsen C, Sauerberg P. DeLapp N, et al. Biochem Biophys Res Commun. 1998 Mar 6;244(1):156-60. doi: 10.1006/bbrc.1998.8235. Biochem Biophys Res Commun. 1998. PMID: 9514902

6

Xanomeline: a novel muscarinic receptor agonist with functional selectivity for M1 receptors.

Shannon HE, Bymaster FP, Calligaro DO, Greenwood B, Mitch CH, Sawyer BD, Ward JS, Wong DT, Olesen PH, Sheardown MJ, Swedberg MD, Suzdak PD, Sauerberg P. Shannon HE, et al. J Pharmacol Exp Ther. 1994 Apr;269(1):271-81. J Pharmacol Exp Ther. 1994. PMID: 7909557

7

Neurochemical effects of the M1 muscarinic agonist xanomeline (LY246708/NNC11-0232).

Bymaster FP, Wong DT, Mitch CH, Ward JS, Calligaro DO, Schoepp DD, Shannon HE, Sheardown MJ, Olesen PH, Suzdak PD, Swedberg MD, Sauerberg P. Bymaster FP, et al. Among authors: shannon he. J Pharmacol Exp Ther. 1994 Apr;269(1):282-9. J Pharmacol Exp Ther. 1994. PMID: 7909558

8

In vivo pharmacology of butylthio[2.2.2] (LY297802 / NNC11-1053), an orally acting antinociceptive muscarinic agonist.

Shannon HE, Womer DE, Bymaster FP, Calligaro DO, DeLapp NC, Mitch CH, Ward JS, Whitesitt CA, Swedberg MD, Sheardown MJ, Fink-Jensen A, Olesen PH, Rimvall K, Sauerberg P. Shannon HE, et al. Life Sci. 1997;60(13-14):969-76. doi: 10.1016/s0024-3205(97)00036-2. Life Sci. 1997. PMID: 9121363 Review.

9

Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects.

Bymaster FP, Carter PA, Peters SC, Zhang W, Ward JS, Mitch CH, Calligaro DO, Whitesitt CA, DeLapp N, Shannon HE, Rimvall K, Jeppesen L, Sheardown MJ, Fink-Jensen A, Sauerberg P. Bymaster FP, et al. Among authors: shannon he. Brain Res. 1998 Jun 8;795(1-2):179-90. doi: 10.1016/s0006-8993(98)00267-4. Brain Res. 1998. PMID: 9622623

10

Potential role of muscarinic receptors in schizophrenia.

Bymaster FP, Shannon HE, Rasmussen K, DeLapp NW, Ward JS, Calligaro DO, Mitch CH, Whitesitt C, Ludvigsen TS, Sheardown M, Swedberg M, Rasmussen T, Olesen PH, Jeppesen L, Sauerberg P, Fink-Jensen A. Bymaster FP, et al. Among authors: shannon he. Life Sci. 1999;64(6-7):527-34. doi: 10.1016/s0024-3205(98)00597-9. Life Sci. 1999. PMID: 10069519

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