Wu L - Search Results

1

The single sulfur to oxygen substitution in the active site nucleophile of the Yersinia protein-tyrosine phosphatase leads to substantial structural and functional perturbations.

Zhang ZY, Wu L. Zhang ZY, et al. Among authors: wu l. Biochemistry. 1997 Feb 11;36(6):1362-9. doi: 10.1021/bi9624043. Biochemistry. 1997. PMID: 9063884

2

Structure-based discovery of small molecule inhibitors targeted to protein tyrosine phosphatase 1B.

Sarmiento M, Wu L, Keng YF, Song L, Luo Z, Huang Z, Wu GZ, Yuan AK, Zhang ZY. Sarmiento M, et al. Among authors: wu gz, wu l. J Med Chem. 2000 Jan 27;43(2):146-55. doi: 10.1021/jm990329z. J Med Chem. 2000. PMID: 10649970

3

Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.

Sarmiento M, Puius YA, Vetter SW, Keng YF, Wu L, Zhao Y, Lawrence DS, Almo SC, Zhang ZY. Sarmiento M, et al. Among authors: wu l. Biochemistry. 2000 Jul 18;39(28):8171-9. doi: 10.1021/bi000319w. Biochemistry. 2000. PMID: 10889023

4

Thermodynamic study of ligand binding to protein-tyrosine phosphatase 1B and its substrate-trapping mutants.

Zhang YL, Yao ZJ, Sarmiento M, Wu L, Burke TR Jr, Zhang ZY. Zhang YL, et al. Among authors: wu l. J Biol Chem. 2000 Nov 3;275(44):34205-12. doi: 10.1074/jbc.M004490200. J Biol Chem. 2000. PMID: 10952978 Free article.

5

Why is phosphonodifluoromethyl phenylalanine a more potent inhibitory moiety than phosphonomethyl phenylalanine toward protein-tyrosine phosphatases?

Chen L, Wu L, Otaka A, Smyth MS, Roller PP, Burke TR Jr, den Hertog J, Zhang ZY. Chen L, et al. Among authors: wu l. Biochem Biophys Res Commun. 1995 Nov 22;216(3):976-84. doi: 10.1006/bbrc.1995.2716. Biochem Biophys Res Commun. 1995. PMID: 7488220

6

Nature of the transition state of the protein-tyrosine phosphatase-catalyzed reaction.

Hengge AC, Sowa GA, Wu L, Zhang ZY. Hengge AC, et al. Among authors: wu l. Biochemistry. 1995 Oct 31;34(43):13982-7. doi: 10.1021/bi00043a003. Biochemistry. 1995. PMID: 7577995

7

Purification and characterization of the low molecular weight protein tyrosine phosphatase, Stp1, from the fission yeast Schizosaccharomyces pombe.

Zhang ZY, Zhou G, Denu JM, Wu L, Tang X, Mondesert O, Russell P, Butch E, Guan KL. Zhang ZY, et al. Among authors: wu l. Biochemistry. 1995 Aug 22;34(33):10560-8. doi: 10.1021/bi00033a031. Biochemistry. 1995. PMID: 7654712

8

The Cys(X)5Arg catalytic motif in phosphoester hydrolysis.

Zhang ZY, Wang Y, Wu L, Fauman EB, Stuckey JA, Schubert HL, Saper MA, Dixon JE. Zhang ZY, et al. Among authors: wu l. Biochemistry. 1994 Dec 27;33(51):15266-70. doi: 10.1021/bi00255a007. Biochemistry. 1994. PMID: 7803389

9

Transition state and rate-limiting step of the reaction catalyzed by the human dual-specificity phosphatase, VHR.

Zhang ZY, Wu L, Chen L. Zhang ZY, et al. Among authors: wu l. Biochemistry. 1995 Dec 12;34(49):16088-96. doi: 10.1021/bi00049a024. Biochemistry. 1995. PMID: 8519766

10

Probing the function of Asp128 in the lower molecular weight protein-tyrosine phosphatase-catalyzed reaction. A pre-steady-state and steady-state kinetic investigation.

Wu L, Zhang ZY. Wu L, et al. Biochemistry. 1996 Apr 30;35(17):5426-34. doi: 10.1021/bi952885a. Biochemistry. 1996. PMID: 8611532

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