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Concurrent down-regulation of IP prostanoid receptors and the alpha-subunit of the stimulatory guanine-nucleotide-binding protein (Gs) during prolonged exposure of neuroblastoma x glioma cells to prostanoid agonists. Quantification and functional implications.
Adie EJ, Mullaney I, McKenzie FR, Milligan G. Adie EJ, et al. Among authors: milligan g. Biochem J. 1992 Jul 15;285 ( Pt 2)(Pt 2):529-36. doi: 10.1042/bj2850529. Biochem J. 1992. PMID: 1379045 Free PMC article.
The remaining receptors were capable of interacting with the stimulatory G-protein (Gs) of the adenylate cyclase cascade, as saturation analysis of the binding of [3H]PGE1 indicated that they had a similar affinity for the 3H-labelled ligand, and because the specific bindi …
The remaining receptors were capable of interacting with the stimulatory G-protein (Gs) of the adenylate cyclase cascade, as saturati …
Agonist-dependent, cholera toxin-catalyzed ADP-ribosylation of pertussis toxin-sensitive G-proteins following transfection of the human alpha 2-C10 adrenergic receptor into rat 1 fibroblasts. Evidence for the direct interaction of a single receptor with two pertussis toxin-sensitive G-proteins, Gi2 and Gi3.
Milligan G, Carr C, Gould GW, Mullaney I, Lavan BE. Milligan G, et al. J Biol Chem. 1991 Apr 5;266(10):6447-55. J Biol Chem. 1991. PMID: 1848855 Free article.
789 results