Srinivasula SM - Search Results

1

Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases.

Srinivasula SM, Ahmad M, Fernandes-Alnemri T, Litwack G, Alnemri ES. Srinivasula SM, et al. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14486-91. doi: 10.1073/pnas.93.25.14486. Proc Natl Acad Sci U S A. 1996. PMID: 8962078 Free PMC article.

2

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.

Fernandes-Alnemri T, Armstrong RC, Krebs J, Srinivasula SM, Wang L, Bullrich F, Fritz LC, Trapani JA, Tomaselli KJ, Litwack G, Alnemri ES. Fernandes-Alnemri T, et al. Among authors: srinivasula sm. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7464-9. doi: 10.1073/pnas.93.15.7464. Proc Natl Acad Sci U S A. 1996. PMID: 8755496 Free PMC article.

3

The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32.

Srinivasula SM, Fernandes-Alnemri T, Zangrilli J, Robertson N, Armstrong RC, Wang L, Trapani JA, Tomaselli KJ, Litwack G, Alnemri ES. Srinivasula SM, et al. J Biol Chem. 1996 Oct 25;271(43):27099-106. doi: 10.1074/jbc.271.43.27099. J Biol Chem. 1996. PMID: 8900201 Free article.

4

Spodoptera frugiperda caspase-1, a novel insect death protease that cleaves the nuclear immunophilin FKBP46, is the target of the baculovirus antiapoptotic protein p35.

Ahmad M, Srinivasula SM, Wang L, Litwack G, Fernandes-Alnemri T, Alnemri ES. Ahmad M, et al. Among authors: srinivasula sm. J Biol Chem. 1997 Jan 17;272(3):1421-4. doi: 10.1074/jbc.272.3.1421. J Biol Chem. 1997. PMID: 8999805 Free article.

5

CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP.

Ahmad M, Srinivasula SM, Wang L, Talanian RV, Litwack G, Fernandes-Alnemri T, Alnemri ES. Ahmad M, et al. Among authors: srinivasula sm. Cancer Res. 1997 Feb 15;57(4):615-9. Cancer Res. 1997. PMID: 9044836

6

FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis.

Srinivasula SM, Ahmad M, Ottilie S, Bullrich F, Banks S, Wang Y, Fernandes-Alnemri T, Croce CM, Litwack G, Tomaselli KJ, Armstrong RC, Alnemri ES. Srinivasula SM, et al. J Biol Chem. 1997 Jul 25;272(30):18542-5. doi: 10.1074/jbc.272.30.18542. J Biol Chem. 1997. PMID: 9228018 Free article.

7

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction.

Hegde R, Srinivasula SM, Zhang Z, Wassell R, Mukattash R, Cilenti L, DuBois G, Lazebnik Y, Zervos AS, Fernandes-Alnemri T, Alnemri ES. Hegde R, et al. Among authors: srinivasula sm. J Biol Chem. 2002 Jan 4;277(1):432-8. doi: 10.1074/jbc.M109721200. Epub 2001 Oct 17. J Biol Chem. 2002. PMID: 11606597 Free article.

8

Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria.

Guo Y, Srinivasula SM, Druilhe A, Fernandes-Alnemri T, Alnemri ES. Guo Y, et al. Among authors: srinivasula sm. J Biol Chem. 2002 Apr 19;277(16):13430-7. doi: 10.1074/jbc.M108029200. Epub 2002 Feb 6. J Biol Chem. 2002. PMID: 11832478 Free article.

9

Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2.

Srinivasula SM, Gupta S, Datta P, Zhang Z, Hegde R, Cheong N, Fernandes-Alnemri T, Alnemri ES. Srinivasula SM, et al. J Biol Chem. 2003 Aug 22;278(34):31469-72. doi: 10.1074/jbc.C300240200. Epub 2003 Jun 30. J Biol Chem. 2003. PMID: 12835328 Free article.

10

The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity.

Gupta S, Singh R, Datta P, Zhang Z, Orr C, Lu Z, Dubois G, Zervos AS, Meisler MH, Srinivasula SM, Fernandes-Alnemri T, Alnemri ES. Gupta S, et al. Among authors: srinivasula sm. J Biol Chem. 2004 Oct 29;279(44):45844-54. doi: 10.1074/jbc.M404940200. Epub 2004 Aug 4. J Biol Chem. 2004. PMID: 15294909 Free article.

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