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High-dose epirubicin, preceded by dexrazoxane, given in combination with paclitaxel plus filgrastim provides an effective mobilizing regimen to support three courses of high-dose dense chemotherapy in patients with high-risk stage II-IIIA breast cancer.
De Giorgi U, Rosti G, Zaniboni A, Ballardini M, Minzi MR, Baioni M, Ferrari E, Zornetta L, Marangolo M. De Giorgi U, et al. Among authors: zornetta l. Bone Marrow Transplant. 2003 Aug;32(3):251-5. doi: 10.1038/sj.bmt.1704125. Bone Marrow Transplant. 2003. PMID: 12858195 Clinical Trial.