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The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32.
Srinivasula SM, Fernandes-Alnemri T, Zangrilli J, Robertson N, Armstrong RC, Wang L, Trapani JA, Tomaselli KJ, Litwack G, Alnemri ES. Srinivasula SM, et al. Among authors: trapani ja. J Biol Chem. 1996 Oct 25;271(43):27099-106. doi: 10.1074/jbc.271.43.27099. J Biol Chem. 1996. PMID: 8900201 Free article.
In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.
Fernandes-Alnemri T, Armstrong RC, Krebs J, Srinivasula SM, Wang L, Bullrich F, Fritz LC, Trapani JA, Tomaselli KJ, Litwack G, Alnemri ES. Fernandes-Alnemri T, et al. Among authors: trapani ja. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7464-9. doi: 10.1073/pnas.93.15.7464. Proc Natl Acad Sci U S A. 1996. PMID: 8755496 Free PMC article.
The perforin pore facilitates the delivery of cationic cargos.
Stewart SE, Kondos SC, Matthews AY, D'Angelo ME, Dunstone MA, Whisstock JC, Trapani JA, Bird PI. Stewart SE, et al. Among authors: trapani ja. J Biol Chem. 2014 Mar 28;289(13):9172-81. doi: 10.1074/jbc.M113.544890. Epub 2014 Feb 20. J Biol Chem. 2014. PMID: 24558045 Free PMC article.
Granzyme M mediates a novel form of perforin-dependent cell death.
Kelly JM, Waterhouse NJ, Cretney E, Browne KA, Ellis S, Trapani JA, Smyth MJ. Kelly JM, et al. Among authors: trapani ja. J Biol Chem. 2004 May 21;279(21):22236-42. doi: 10.1074/jbc.M401670200. Epub 2004 Mar 17. J Biol Chem. 2004. PMID: 15028722 Free article.
344 results