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Complete analysis of the presenilin 1 gene in early onset Alzheimer's disease.
Hutton M, Busfield F, Wragg M, Crook R, Perez-Tur J, Clark RF, Prihar G, Talbot C, Phillips H, Wright K, Baker M, Lendon C, Duff K, Martinez A, Houlden H, Nichols A, Karran E, Roberts G, Roques P, Rossor M, Venter JC, Adams MD, Cline RT, Phillips CA, Goate A, et al. Hutton M, et al. Neuroreport. 1996 Feb 29;7(3):801-5. doi: 10.1097/00001756-199602290-00029. Neuroreport. 1996. PMID: 8733749
Polymorphism in AACT gene may lower age of onset of Alzheimer's disease.
Talbot C, Houlden H, Craddock N, Crook R, Hutton M, Lendon C, Prihar G, Morris JC, Hardy J, Goate A. Talbot C, et al. Among authors: hutton m. Neuroreport. 1996 Jan 31;7(2):534-6. doi: 10.1097/00001756-199601310-00038. Neuroreport. 1996. PMID: 8730823 Clinical Trial.
Structure and alternative splicing of the presenilin-2 gene.
Prihar G, Fuldner RA, Perez-Tur J, Lincoln S, Duff K, Crook R, Hardy J, Philips CA, Venter C, Talbot C, Clark RF, Goate A, Li J, Potter H, Karran E, Roberts GW, Hutton M, Adams MD. Prihar G, et al. Among authors: hutton m. Neuroreport. 1996 Jul 8;7(10):1680-4. doi: 10.1097/00001756-199607080-00031. Neuroreport. 1996. PMID: 8904781
The role of presenilin 1 in the genetics of Alzheimer's disease.
Clark RF, Hutton M, Talbot C, Wragg M, Lendon C, Busfield F, Han SW, Perez-Tur J, Adams M, Fuldner R, Roberts G, Karran E, Hardy J, Goate A. Clark RF, et al. Among authors: hutton m. Cold Spring Harb Symp Quant Biol. 1996;61:551-8. Cold Spring Harb Symp Quant Biol. 1996. PMID: 9246481
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1.
Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, Hardy J, Younkin S. Duff K, et al. Among authors: hutton m. Nature. 1996 Oct 24;383(6602):710-3. doi: 10.1038/383710a0. Nature. 1996. PMID: 8878479
481 results