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Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16.
Wijnen J, Khan PM, Vasen H, Menko F, van der Klift H, van den Broek M, van Leeuwen-Cornelisse I, Nagengast F, Meijers-Heijboer EJ, Lindhout D, Griffioen G, Cats A, Kleibeuker J, Varesco L, Bertario L, Bisgaard ML, Mohr J, Kolodner R, Fodde R. Wijnen J, et al. Among authors: cats a. Am J Hum Genet. 1996 Feb;58(2):300-7. Am J Hum Genet. 1996. PMID: 8571956 Free PMC article.
What is the appropriate screening protocol in Lynch syndrome?
de Jong AE, Nagengast FM, Kleibeuker JH, van de Meeberg PC, van Wijk HJ, Cats A, Griffioen G, Vasen HF. de Jong AE, et al. Among authors: cats a. Fam Cancer. 2006;5(4):373-8. doi: 10.1007/s10689-006-0008-6. Epub 2006 Jul 7. Fam Cancer. 2006. PMID: 16826316
421 results