Williams DA - Search Results

1

Increasing DNA repair methyltransferase levels via bone marrow stem cell transduction rescues mice from the toxic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea, a chemotherapeutic alkylating agent.

Maze R, Carney JP, Kelley MR, Glassner BJ, Williams DA, Samson L. Maze R, et al. Among authors: williams da. Proc Natl Acad Sci U S A. 1996 Jan 9;93(1):206-10. doi: 10.1073/pnas.93.1.206. Proc Natl Acad Sci U S A. 1996. PMID: 8552605 Free PMC article.

2

Comparative effects of in vivo treatment using interleukin-11 and stem cell factor on reconstitution in mice after bone marrow transplantation.

Du XX, Keller D, Maze R, Williams DA. Du XX, et al. Among authors: williams da. Blood. 1993 Aug 1;82(3):1016-22. Blood. 1993. PMID: 7687888 Free article.

3

Retrovirus-mediated expression of a DNA repair protein in bone marrow protects hematopoietic cells from nitrosourea-induced toxicity in vitro and in vivo.

Moritz T, Mackay W, Glassner BJ, Williams DA, Samson L. Moritz T, et al. Among authors: williams da. Cancer Res. 1995 Jun 15;55(12):2608-14. Cancer Res. 1995. PMID: 7780976

4

Increased survival and multilineage hematopoietic protection from delayed and severe myelosuppressive effects of a nitrosourea with recombinant interleukin-11.

Maze R, Moritz T, Williams DA. Maze R, et al. Among authors: williams da. Cancer Res. 1994 Sep 15;54(18):4947-51. Cancer Res. 1994. PMID: 8069861

5

Reversal of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced severe immunodeficiency by transduction of murine long-lived hemopoietic progenitor cells using O6-methylguanine DNA methyltransferase complementary DNA.

Maze R, Kapur R, Kelley MR, Hansen WK, Oh SY, Williams DA. Maze R, et al. Among authors: williams da. J Immunol. 1997 Jan 15;158(2):1006-13. J Immunol. 1997. PMID: 8993023

6

Establishing chemoresistance in hematopoietic progenitor cells.

Maze R, Hanenberg H, Williams DA. Maze R, et al. Among authors: williams da. Mol Med Today. 1997 Aug;3(8):350-8. doi: 10.1016/s1357-4310(97)01094-0. Mol Med Today. 1997. PMID: 9269688 Review.

7

Creation of a fully functional human chimeric DNA repair protein. Combining O6-methylguanine DNA methyltransferase (MGMT) and AP endonuclease (APE/redox effector factor 1 (Ref 1)) DNA repair proteins.

Hansen WK, Deutsch WA, Yacoub A, Xu Y, Williams DA, Kelley MR. Hansen WK, et al. Among authors: williams da. J Biol Chem. 1998 Jan 9;273(2):756-62. doi: 10.1074/jbc.273.2.756. J Biol Chem. 1998. PMID: 9422728 Free article.

8

Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment.

Maze R, Kurpad C, Pegg AE, Erickson LC, Williams DA. Maze R, et al. Among authors: williams da. J Pharmacol Exp Ther. 1999 Sep;290(3):1467-74. J Pharmacol Exp Ther. 1999. PMID: 10454526

9

Protection of hematopoietic cells against combined O6-benzylguanine and chloroethylnitrosourea treatment by mutant forms of O6-methylguanine DNA methyltransferase.

Williams DA, Maze R, Kurpad C, Pegg A, Erickson LC. Williams DA, et al. Bone Marrow Transplant. 2000 May;25 Suppl 2:S105-9. doi: 10.1038/sj.bmt.1702367. Bone Marrow Transplant. 2000. PMID: 10933201

10

Protection of mammalian cells against chemotherapeutic agents thiotepa, 1,3-N,N'-bis(2-chloroethyl)-N-nitrosourea, and mafosfamide using the DNA base excision repair genes Fpg and alpha-hOgg1: implications for protective gene therapy applications.

Xu Y, Hansen WK, Rosenquist TA, Williams DA, Limp-Foster M, Kelley MR. Xu Y, et al. Among authors: williams da. J Pharmacol Exp Ther. 2001 Mar;296(3):825-31. J Pharmacol Exp Ther. 2001. PMID: 11181913

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