Johnson LN - Search Results

1

Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds.

Watson KA, Mitchell EP, Johnson LN, Son JC, Bichard CJ, Orchard MG, Fleet GW, Oikonomakos NG, Leonidas DD, Kontou M, et al. Watson KA, et al. Among authors: johnson ln. Biochemistry. 1994 May 17;33(19):5745-58. doi: 10.1021/bi00185a011. Biochemistry. 1994. PMID: 8180201

2

Substrate-cofactor interactions for glycogen phosphorylase b: a binding study in the crystal with heptenitol and heptulose 2-phosphate.

McLaughlin PJ, Stuart DI, Klein HW, Oikonomakos NG, Johnson LN. McLaughlin PJ, et al. Among authors: johnson ln. Biochemistry. 1984 Nov 20;23(24):5862-73. doi: 10.1021/bi00319a028. Biochemistry. 1984. PMID: 6441595

3

The design of potential antidiabetic drugs: experimental investigation of a number of beta-D-glucose analogue inhibitors of glycogen phosphorylase.

Oikonomakos NG, Kontou M, Zographos SE, Tsitoura HS, Johnson LN, Watson KA, Mitchell EP, Fleet GW, Son JC, Bichard CJ, et al. Oikonomakos NG, et al. Among authors: johnson ln. Eur J Drug Metab Pharmacokinet. 1994 Jul-Sep;19(3):185-92. doi: 10.1007/BF03188920. Eur J Drug Metab Pharmacokinet. 1994. PMID: 7867660

4

Crystallographic binding studies on the allosteric inhibitor glucose-6-phosphate to T state glycogen phosphorylase b.

Johnson LN, Snape P, Martin JL, Acharya KR, Barford D, Oikonomakos NG. Johnson LN, et al. J Mol Biol. 1993 Jul 5;232(1):253-67. doi: 10.1006/jmbi.1993.1380. J Mol Biol. 1993. PMID: 8331662

5

Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.

Mitchell EP, Withers SG, Ermert P, Vasella AT, Garman EF, Oikonomakos NG, Johnson LN. Mitchell EP, et al. Among authors: johnson ln. Biochemistry. 1996 Jun 11;35(23):7341-55. doi: 10.1021/bi960072w. Biochemistry. 1996. PMID: 8652510

6

The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding.

Gregoriou M, Noble ME, Watson KA, Garman EF, Krulle TM, de la Fuente C, Fleet GW, Oikonomakos NG, Johnson LN. Gregoriou M, et al. Among authors: johnson ln. Protein Sci. 1998 Apr;7(4):915-27. doi: 10.1002/pro.5560070409. Protein Sci. 1998. PMID: 9568898 Free PMC article.

7

The crystal structure of the Escherichia coli maltodextrin phosphorylase-acarbose complex.

O'Reilly M, Watson KA, Johnson LN. O'Reilly M, et al. Among authors: johnson ln. Biochemistry. 1999 Apr 27;38(17):5337-45. doi: 10.1021/bi9828573. Biochemistry. 1999. PMID: 10220320

8

Glucose analogue inhibitors of glycogen phosphorylase: from crystallographic analysis to drug prediction using GRID force-field and GOLPE variable selection.

Watson KA, Mitchell EP, Johnson LN, Cruciani G, Son JC, Bichard CJ, Fleet GW, Oikonomakos NG, Kontou M, Zographos SE. Watson KA, et al. Among authors: johnson ln. Acta Crystallogr D Biol Crystallogr. 1995 Jul 1;51(Pt 4):458-72. doi: 10.1107/S090744499401348X. Acta Crystallogr D Biol Crystallogr. 1995. PMID: 15299833

9

Pyridoxal phosphate site in glycogen phosphorylase b: structure in native enzyme and in three derivatives with modified cofactors.

Oikonomakos NG, Johnson LN, Acharya KR, Stuart DI, Barford D, Hajdu J, Varvill KM, Melpidou AE, Papageorgiou T, Graves DJ, et al. Oikonomakos NG, et al. Among authors: johnson ln. Biochemistry. 1987 Dec 15;26(25):8381-9. doi: 10.1021/bi00399a053. Biochemistry. 1987. PMID: 3126802

10

Channels at the catalytic site of glycogen phosphorylase b: binding and kinetic studies with the beta-glycosidase inhibitor D-gluconohydroximo-1,5-lactone N-phenylurethane.

Barford D, Schwabe JW, Oikonomakos NG, Acharya KR, Hajdu J, Papageorgiou AC, Martin JL, Knott JC, Vasella A, Johnson LN. Barford D, et al. Among authors: johnson ln. Biochemistry. 1988 Sep 6;27(18):6733-41. doi: 10.1021/bi00418a014. Biochemistry. 1988. PMID: 3143403

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