Smith SA - Search Results

1

[[omega-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents.

Cantello BC, Cawthorne MA, Cottam GP, Duff PT, Haigh D, Hindley RM, Lister CA, Smith SA, Thurlby PL. Cantello BC, et al. Among authors: smith sa. J Med Chem. 1994 Nov 11;37(23):3977-85. doi: 10.1021/jm00049a017. J Med Chem. 1994. PMID: 7966158

2

Non-thiazolidinedione antihyperglycaemic agents. Part 3: The effects of stereochemistry on the potency of alpha-methoxy-beta-phenylpropanoic acids.

Haigh D, Allen G, Birrell HC, Buckle DR, Cantello BC, Eggleston DS, Haltiwanger RC, Holder JC, Lister CA, Pinto IL, Rami HK, Sime JT, Smith SA, Sweeney JD. Haigh D, et al. Among authors: smith sa. Bioorg Med Chem. 1999 May;7(5):821-30. doi: 10.1016/s0968-0896(99)00034-6. Bioorg Med Chem. 1999. PMID: 10400335

3

BRL 35135, a potent and selective atypical beta-adrenoceptor agonist.

Cawthorne MA, Sennitt MV, Arch JR, Smith SA. Cawthorne MA, et al. Among authors: smith sa. Am J Clin Nutr. 1992 Jan;55(1 Suppl):252S-257S. doi: 10.1093/ajcn/55.1.252s. Am J Clin Nutr. 1992. PMID: 1345889 Review.

4

Repeat treatment of obese mice with BRL 49653, a new potent insulin sensitizer, enhances insulin action in white adipocytes. Association with increased insulin binding and cell-surface GLUT4 as measured by photoaffinity labeling.

Young PW, Cawthorne MA, Coyle PJ, Holder JC, Holman GD, Kozka IJ, Kirkham DM, Lister CA, Smith SA. Young PW, et al. Among authors: smith sa. Diabetes. 1995 Sep;44(9):1087-92. doi: 10.2337/diab.44.9.1087. Diabetes. 1995. PMID: 7657033

5

Antidiabetic efficacy of BRL 49653, a potent orally active insulin sensitizing agent, assessed in the C57BL/KsJ db/db diabetic mouse by non-invasive 1H NMR studies of urine.

Connor SC, Hughes MG, Moore G, Lister CA, Smith SA. Connor SC, et al. Among authors: smith sa. J Pharm Pharmacol. 1997 Mar;49(3):336-44. doi: 10.1111/j.2042-7158.1997.tb06808.x. J Pharm Pharmacol. 1997. PMID: 9231358

6

Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma.

Young PW, Buckle DR, Cantello BC, Chapman H, Clapham JC, Coyle PJ, Haigh D, Hindley RM, Holder JC, Kallender H, Latter AJ, Lawrie KW, Mossakowska D, Murphy GJ, Roxbee Cox L, Smith SA. Young PW, et al. Among authors: smith sa. J Pharmacol Exp Ther. 1998 Feb;284(2):751-9. J Pharmacol Exp Ther. 1998. PMID: 9454824

7

Rosiglitazone prevents the onset of hyperglycaemia and proteinuria in the Zucker diabetic fatty rat.

Smith SA, Lister CA, Toseland CD, Buckingham RE. Smith SA, et al. Diabetes Obes Metab. 2000 Dec;2(6):363-72. doi: 10.1046/j.1463-1326.2000.00099.x. Diabetes Obes Metab. 2000. PMID: 11225966

8

Effects of BRL 35135, a beta-adrenoceptor agonist with novel selectivity, on glucose tolerance and insulin sensitivity in obese subjects.

Mitchell TH, Ellis RD, Smith SA, Robb G, Cawthorne MA. Mitchell TH, et al. Among authors: smith sa. Int J Obes. 1989;13(6):757-66. Int J Obes. 1989. PMID: 2695481

9

The beta-adrenoceptor selectivity profile of BRL 37344 in the pithed rat.

Oriowo MA, Sennitt MV, Smith SA, Ruffolo RR Jr, Cawthorne MA. Oriowo MA, et al. Among authors: smith sa. J Auton Pharmacol. 1994 Oct;14(5):337-44. doi: 10.1111/j.1474-8673.1994.tb00614.x. J Auton Pharmacol. 1994. PMID: 7829538

10

Differential regulation of adipocytokine mRNAs by rosiglitazone in db/db mice.

Moore GB, Chapman H, Holder JC, Lister CA, Piercy V, Smith SA, Clapham JC. Moore GB, et al. Among authors: smith sa. Biochem Biophys Res Commun. 2001 Aug 31;286(4):735-41. doi: 10.1006/bbrc.2001.5460. Biochem Biophys Res Commun. 2001. PMID: 11520059

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