Blankley CJ - Search Results

1

Cholesteryl ester transfer protein inhibition by PD 140195.

Bisgaier CL, Essenburg AD, Minton LL, Homan R, Blankley CJ, White A. Bisgaier CL, et al. Among authors: blankley cj. Lipids. 1994 Dec;29(12):811-8. doi: 10.1007/BF02536247. Lipids. 1994. PMID: 7854005

2

Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents.

Roth BD, Blankley CJ, Hoefle ML, Holmes A, Roark WH, Trivedi BK, Essenburg AD, Kieft KA, Krause BR, Stanfield RL. Roth BD, et al. Among authors: blankley cj. J Med Chem. 1992 May 1;35(9):1609-17. doi: 10.1021/jm00087a016. J Med Chem. 1992. PMID: 1578488

3

Inhibitors of acyl-Coa:cholesterol acyltransferase. 4. A novel series of urea ACAT inhibitors as potential hypocholesterolemic agents.

Trivedi BK, Holmes A, Stoeber TL, Blankley CJ, Roark WH, Picard JA, Shaw MK, Essenburg AD, Stanfield RL, Krause BR. Trivedi BK, et al. Among authors: blankley cj. J Med Chem. 1993 Oct 29;36(22):3300-7. doi: 10.1021/jm00074a011. J Med Chem. 1993. PMID: 8230120

4

Inhibitors of acyl-CoA:cholesterol acyltransferase. 5. Identification and structure-activity relationships of novel beta-ketoamides as hypocholesterolemic agents.

Augelli-Szafran CE, Blankley CJ, Roth BD, Trivedi BK, Bousley RF, Essenburg AD, Hamelehle KL, Krause BR, Stanfield RL. Augelli-Szafran CE, et al. Among authors: blankley cj. J Med Chem. 1993 Oct 1;36(20):2943-9. doi: 10.1021/jm00072a014. J Med Chem. 1993. PMID: 8411011

5

Bioisosterism in drug design: identification of and structure-activity relationships in a series of glycine anilide ACAT inhibitors.

Roark WH, Padia J, Bolton GL, Blankley CJ, Essenburg AD, Stanfield RL, Bousley RF, Krause BR, Roth BD. Roark WH, et al. Among authors: blankley cj. Bioorg Med Chem. 1995 Jan;3(1):29-39. doi: 10.1016/0968-0896(94)00144-r. Bioorg Med Chem. 1995. PMID: 8612044

6

Heterocyclic ureas: inhibitors of acyl-CoA:cholesterol O-acyltransferase as hypocholesterolemic agents.

White AD, Creswell MW, Chucholowski AW, Blankley CJ, Wilson MW, Bousley RF, Essenburg AD, Hamelehle KL, Krause BR, Stanfield RL, Dominick MA, Neub M. White AD, et al. Among authors: blankley cj. J Med Chem. 1996 Oct 25;39(22):4382-95. doi: 10.1021/jm960404v. J Med Chem. 1996. PMID: 8893833

7

Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. A divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types.

Klutchko S, Blankley CJ, Fleming RW, Hinkley JM, Werner AE, Nordin I, Holmes A, Hoefle ML, Cohen DM, Essenburg AD, et al. Klutchko S, et al. Among authors: blankley cj. J Med Chem. 1986 Oct;29(10):1953-61. doi: 10.1021/jm00160a026. J Med Chem. 1986. PMID: 3020249

8

Inhibitors of acyl-CoA:cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. 8. Incorporation of amide or amine functionalities into a series of disubstituted ureas and carbamates. Effects on ACAT inhibition in vitro and efficacy in vivo.

O'Brien PM, Sliskovic DR, Blankley CJ, Roth BD, Wilson MW, Hamelehle KL, Krause BR, Stanfield RL. O'Brien PM, et al. Among authors: blankley cj. J Med Chem. 1994 Jun 10;37(12):1810-22. doi: 10.1021/jm00038a010. J Med Chem. 1994. PMID: 8021920

9

Inhibitors of cholesterol biosynthesis. 6. trans-6-[2-(2-N-heteroaryl-3,5-disubstituted- pyrazol-4-yl)ethyl/ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-ones.

Sliskovic DR, Blankley CJ, Krause BR, Newton RS, Picard JA, Roark WH, Roth BD, Sekerke C, Shaw MK, Stanfield RL. Sliskovic DR, et al. Among authors: blankley cj. J Med Chem. 1992 May 29;35(11):2095-103. doi: 10.1021/jm00089a022. J Med Chem. 1992. PMID: 1597859

10

Relationship between tissue selectivity and lipophilicity for inhibitors of HMG-CoA reductase.

Roth BD, Bocan TM, Blankley CJ, Chucholowski AW, Creger PL, Creswell MW, Ferguson E, Newton RS, O'Brien P, Picard JA, et al. Roth BD, et al. Among authors: blankley cj. J Med Chem. 1991 Jan;34(1):463-6. doi: 10.1021/jm00105a071. J Med Chem. 1991. PMID: 1992149 No abstract available.

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