Debnath ML - Search Results

1

Inactivity of phosphoethanolamine, an endogenous GABA analog decreased in Alzheimer's disease, at GABA binding sites.

Klunk WE, Debnath ML, McClure RJ, Pettegrew JW. Klunk WE, et al. Among authors: debnath ml. Life Sci. 1995;56(26):2377-83. doi: 10.1016/0024-3205(95)00231-t. Life Sci. 1995. PMID: 7791524

2

Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain.

Klunk WE, Wang Y, Huang GF, Debnath ML, Holt DP, Mathis CA. Klunk WE, et al. Among authors: debnath ml. Life Sci. 2001 Aug 17;69(13):1471-84. doi: 10.1016/s0024-3205(01)01232-2. Life Sci. 2001. PMID: 11554609

3

Synthesis and evaluation of 2-(3'-iodo-4'-aminophenyl)-6-hydroxybenzothiazole for in vivo quantitation of amyloid deposits in Alzheimer's disease.

Wang Y, Klunk WE, Huang GF, Debnath ML, Holt DP, Mathis CA. Wang Y, et al. Among authors: debnath ml. J Mol Neurosci. 2002 Aug-Oct;19(1-2):11-6. doi: 10.1007/s12031-002-0004-8. J Mol Neurosci. 2002. PMID: 12212766

4

Development of small molecule probes for the beta-amyloid protein of Alzheimer's disease.

Klunk WE, Debnath ML, Pettegrew JW. Klunk WE, et al. Among authors: debnath ml. Neurobiol Aging. 1994 Nov-Dec;15(6):691-8. doi: 10.1016/0197-4580(94)90050-7. Neurobiol Aging. 1994. PMID: 7891823

5

Chrysamine-G binding to Alzheimer and control brain: autopsy study of a new amyloid probe.

Klunk WE, Debnath ML, Pettegrew JW. Klunk WE, et al. Among authors: debnath ml. Neurobiol Aging. 1995 Jul-Aug;16(4):541-8. doi: 10.1016/0197-4580(95)00058-m. Neurobiol Aging. 1995. PMID: 8544903

6

The binding of 2-(4'-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component.

Klunk WE, Wang Y, Huang GF, Debnath ML, Holt DP, Shao L, Hamilton RL, Ikonomovic MD, DeKosky ST, Mathis CA. Klunk WE, et al. Among authors: debnath ml. J Neurosci. 2003 Mar 15;23(6):2086-92. doi: 10.1523/JNEUROSCI.23-06-02086.2003. J Neurosci. 2003. PMID: 12657667 Free PMC article.

7

Effects of lipophilicity on the affinity and nonspecific binding of iodinated benzothiazole derivatives.

Wang Y, Mathis CA, Huang GF, Debnath ML, Holt DP, Shao L, Klunk WE. Wang Y, et al. Among authors: debnath ml. J Mol Neurosci. 2003;20(3):255-60. doi: 10.1385/JMN:20:3:255. J Mol Neurosci. 2003. PMID: 14501005

8

Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain.

Klunk WE, Lopresti BJ, Ikonomovic MD, Lefterov IM, Koldamova RP, Abrahamson EE, Debnath ML, Holt DP, Huang GF, Shao L, DeKosky ST, Price JC, Mathis CA. Klunk WE, et al. Among authors: debnath ml. J Neurosci. 2005 Nov 16;25(46):10598-606. doi: 10.1523/JNEUROSCI.2990-05.2005. J Neurosci. 2005. PMID: 16291932 Free PMC article.

9

X-34 labeling of abnormal protein aggregates during the progression of Alzheimer's disease.

Ikonomovic MD, Abrahamson EE, Isanski BA, Debnath ML, Mathis CA, Dekosky ST, Klunk WE. Ikonomovic MD, et al. Among authors: debnath ml. Methods Enzymol. 2006;412:123-44. doi: 10.1016/S0076-6879(06)12009-1. Methods Enzymol. 2006. PMID: 17046656 Review.

10

Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease.

Ikonomovic MD, Klunk WE, Abrahamson EE, Mathis CA, Price JC, Tsopelas ND, Lopresti BJ, Ziolko S, Bi W, Paljug WR, Debnath ML, Hope CE, Isanski BA, Hamilton RL, DeKosky ST. Ikonomovic MD, et al. Among authors: debnath ml. Brain. 2008 Jun;131(Pt 6):1630-45. doi: 10.1093/brain/awn016. Epub 2008 Mar 12. Brain. 2008. PMID: 18339640 Free PMC article.

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