Kondo K - Search Results

1

Discovery of potent cyclic GMP phosphodiesterase inhibitors. 2-Pyridyl- and 2-imidazolylquinazolines possessing cyclic GMP phosphodiesterase and thromboxane synthesis inhibitory activities.

Lee SJ, Konishi Y, Yu DT, Miskowski TA, Riviello CM, Macina OT, Frierson MR, Kondo K, Sugitani M, Sircar JC, et al. Lee SJ, et al. Among authors: kondo k. J Med Chem. 1995 Sep 1;38(18):3547-57. doi: 10.1021/jm00018a014. J Med Chem. 1995. PMID: 7658441

2

Design and synthesis of a selective EP4-receptor agonist. Part 1: discovery of 3,7-dithiaPGE1 derivatives and identification of their omega chains.

Maruyama T, Asada M, Shiraishi T, Egashira H, Yoshida H, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Maruyama T, et al. Among authors: kondo k. Bioorg Med Chem. 2002 Apr;10(4):975-88. doi: 10.1016/s0968-0896(01)00351-0. Bioorg Med Chem. 2002. PMID: 11836107

3

Design and synthesis of a selective EP4-receptor agonist. Part 2: 3,7-dithiaPGE1 derivatives with high selectivity.

Maruyama T, Asada M, Shiraishi T, Ishida A, Yoshida H, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Maruyama T, et al. Among authors: kondo k. Bioorg Med Chem. 2002 Apr;10(4):989-1008. doi: 10.1016/s0968-0896(01)00352-2. Bioorg Med Chem. 2002. PMID: 11836108

4

Discovery of new chemical leads for selective EP1 receptor antagonists.

Naganawa A, Saito T, Nagao Y, Egashira H, Iwahashi M, Kambe T, Koketsu M, Yamamoto H, Kobayashi M, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Naganawa A, et al. Among authors: kondo k. Bioorg Med Chem. 2006 Aug 15;14(16):5562-77. doi: 10.1016/j.bmc.2006.04.038. Epub 2006 May 12. Bioorg Med Chem. 2006. PMID: 16697646

5

Design and synthesis of a selective EP4-receptor agonist. Part 3: 16-phenyl-5-thiaPGE(1) and 9-beta-halo derivatives with improved stability.

Maruyama T, Asada M, Shiraishi T, Yoshida H, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Maruyama T, et al. Among authors: kondo k. Bioorg Med Chem. 2002 Jun;10(6):1743-59. doi: 10.1016/s0968-0896(02)00031-7. Bioorg Med Chem. 2002. PMID: 11937333

6

Optimization of sulfonamide derivatives as highly selective EP1 receptor antagonists.

Naganawa A, Matsui T, Ima M, Yoshida K, Tsuruta H, Yamamoto S, Yamamoto H, Okada H, Maruyama T, Nakai H, Kondo K, Toda M. Naganawa A, et al. Among authors: kondo k. Bioorg Med Chem. 2006 Dec 1;14(23):7774-89. doi: 10.1016/j.bmc.2006.08.001. Epub 2006 Aug 22. Bioorg Med Chem. 2006. PMID: 16931028

7

Discovery of heteroaryl sulfonamides as new EP1 receptor selective antagonists.

Naganawa A, Matsui T, Saito T, Ima M, Tatsumi T, Yamamoto S, Murota M, Yamamoto H, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Naganawa A, et al. Among authors: kondo k. Bioorg Med Chem. 2006 Oct 1;14(19):6628-39. doi: 10.1016/j.bmc.2006.05.076. Epub 2006 Jun 19. Bioorg Med Chem. 2006. PMID: 16784865

8

Development of a highly selective EP2-receptor agonist. Part 1: identification of 16-hydroxy-17,17-trimethylene PGE2 derivatives.

Tani K, Naganawa A, Ishida A, Sagawa K, Harada H, Ogawa M, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Tani K, et al. Among authors: kondo k. Bioorg Med Chem. 2002 Apr;10(4):1093-106. doi: 10.1016/s0968-0896(01)00369-8. Bioorg Med Chem. 2002. PMID: 11836120

9

A practical synthesis and biological evaluation of 9-halogenated PGF analogues.

Tani K, Naganawa A, Ishida A, Egashira H, Odagaki Y, Miyazaki T, Hasegawa T, Kawanaka Y, Sagawa K, Harada H, Ogawa M, Maruyama T, Nakai H, Ohuchida S, Kondo K, Toda M. Tani K, et al. Among authors: kondo k. Bioorg Med Chem. 2002 Jun;10(6):1883-94. doi: 10.1016/s0968-0896(02)00008-1. Bioorg Med Chem. 2002. PMID: 11937346

10

Development of a highly selective EP2-receptor agonist. Part 2: identification of 16-hydroxy-17,17-trimethylene 9beta-chloro PGF derivatives.

Tani K, Naganawa A, Ishida A, Egashira H, Sagawa K, Harada H, Ogawa M, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Tani K, et al. Among authors: kondo k. Bioorg Med Chem. 2002 Apr;10(4):1107-14. doi: 10.1016/s0968-0896(01)00370-4. Bioorg Med Chem. 2002. PMID: 11836121

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