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Page 1
A paradigm for drug discovery employing encoded combinatorial libraries.
Burbaum JJ, Ohlmeyer MH, Reader JC, Henderson I, Dillard LW, Li G, Randle TL, Sigal NH, Chelsky D, Baldwin JJ. Burbaum JJ, et al. Among authors: chelsky d. Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):6027-31. doi: 10.1073/pnas.92.13.6027. Proc Natl Acad Sci U S A. 1995. PMID: 7597074 Free PMC article.
Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry.
McMillan K, Adler M, Auld DS, Baldwin JJ, Blasko E, Browne LJ, Chelsky D, Davey D, Dolle RE, Eagen KA, Erickson S, Feldman RI, Glaser CB, Mallari C, Morrissey MM, Ohlmeyer MH, Pan G, Parkinson JF, Phillips GB, Polokoff MA, Sigal NH, Vergona R, Whitlow M, Young TA, Devlin JJ. McMillan K, et al. Among authors: chelsky d. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1506-11. doi: 10.1073/pnas.97.4.1506. Proc Natl Acad Sci U S A. 2000. PMID: 10677491 Free PMC article.
Surfing the piperazine core of tricyclic farnesyltransferase inhibitors.
Rokosz LL, Huang CY, Reader JC, Stauffer TM, Chelsky D, Sigal NH, Ganguly AK, Baldwin JJ. Rokosz LL, et al. Among authors: chelsky d. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5537-43. doi: 10.1016/j.bmcl.2005.08.074. Epub 2005 Oct 3. Bioorg Med Chem Lett. 2005. PMID: 16202593
Corrigendum to "Analytical validation of protein biomarkers for risk of spontaneous preterm birth" [Clin. Mass Spectrom. 3 (2017) 25-38].
Bradford C, Severinsen R, Pugmire T, Rasmussen M, Stoddard K, Uemura Y, Wheelwright S, Mentinova M, Chelsky D, Hunsucker SW, Kearney P, Hickok D, Fleischer TC, Ichetovkin I, Boniface JJ, Critchfield GC, Peltier JM. Bradford C, et al. Among authors: chelsky d. J Mass Spectrom Adv Clin Lab. 2022 Aug 9;25:71. doi: 10.1016/j.jmsacl.2022.07.007. eCollection 2022 Aug. J Mass Spectrom Adv Clin Lab. 2022. PMID: 35969710 Free PMC article.
Longitudinal CSF proteomics identifies NPTX2 as a prognostic biomarker of Alzheimer's disease.
Libiger O, Shaw LM, Watson MH, Nairn AC, Umaña KL, Biarnes MC, Canet-Avilés RM, Jack CR Jr, Breton YA, Cortes L, Chelsky D, Spellman DS, Baker SA, Raghavan N, Potter WZ; Alzheimer's Disease Neuroimaging Initiative (ADNI); Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium, Longitudinal CSF Proteomics Project Team. Libiger O, et al. Among authors: chelsky d. Alzheimers Dement. 2021 Dec;17(12):1976-1987. doi: 10.1002/alz.12353. Epub 2021 May 13. Alzheimers Dement. 2021. PMID: 33984181 Free PMC article.
Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer's disease modification.
Izzo NJ, Yuede CM, LaBarbera KM, Limegrover CS, Rehak C, Yurko R, Waybright L, Look G, Rishton G, Safferstein H, Hamby ME, Williams C, Sadlek K, Edwards HM, Davis CS, Grundman M, Schneider LS, DeKosky ST, Chelsky D, Pike I, Henstridge C, Blennow K, Zetterberg H, LeVine H 3rd, Spires-Jones TL, Cirrito JR, Catalano SM. Izzo NJ, et al. Among authors: chelsky d. Alzheimers Dement. 2021 Aug;17(8):1365-1382. doi: 10.1002/alz.12302. Epub 2021 Feb 8. Alzheimers Dement. 2021. PMID: 33559354 Free PMC article. Clinical Trial.
35 results