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Analysis of ligand binding to the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that lipoprotein lipase and the carboxyl-terminal domain of the receptor-associated protein bind to the same site.
Nielsen MS, Nykjaer A, Warshawsky I, Schwartz AL, Gliemann J. Nielsen MS, et al. Among authors: nykjaer a. J Biol Chem. 1995 Oct 6;270(40):23713-9. doi: 10.1074/jbc.270.40.23713. J Biol Chem. 1995. PMID: 7559542 Free article.
We found complete cross-competition between carboxyl-terminal RAP fragments and fragments of lipoprotein lipase containing the recently identified binding domain for alpha 2MR/LRP (Nykjaer, A., Nielsen, M., Lookene, A., Meyer, N., Roigaard, H., Etzerodt, M., …
We found complete cross-competition between carboxyl-terminal RAP fragments and fragments of lipoprotein lipase containing the recently iden …
Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes.
Nykjaer A, Petersen CM, Møller B, Jensen PH, Moestrup SK, Holtet TL, Etzerodt M, Thøgersen HC, Munch M, Andreasen PA, et al. Nykjaer A, et al. J Biol Chem. 1992 Jul 25;267(21):14543-6. J Biol Chem. 1992. PMID: 1378833 Free article.
Urokinase receptors in human monocytes.
Nykjaer A, Petersen CM, Christensen EI, Davidsen O, Gliemann J. Nykjaer A, et al. Biochim Biophys Acta. 1990 May 22;1052(3):399-407. doi: 10.1016/0167-4889(90)90149-8. Biochim Biophys Acta. 1990. PMID: 2162216
Alpha 2-macroglobulin-proteinase complexes, plasminogen activator inhibitor type-1-plasminogen activator complexes, and receptor-associated protein bind to a region of the alpha 2-macroglobulin receptor containing a cluster of eight complement-type repeats.
Moestrup SK, Holtet TL, Etzerodt M, Thøgersen HC, Nykjaer A, Andreasen PA, Rasmussen HH, Sottrup-Jensen L, Gliemann J. Moestrup SK, et al. Among authors: nykjaer a. J Biol Chem. 1993 Jun 25;268(18):13691-6. J Biol Chem. 1993. PMID: 7685767 Free article.
Regions involved in binding of urokinase-type-1 inhibitor complex and pro-urokinase to the endocytic alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that the urokinase receptor protects pro-urokinase against binding to the endocytic receptor.
Nykjaer A, Kjøller L, Cohen RL, Lawrence DA, Garni-Wagner BA, Todd RF 3rd, van Zonneveld AJ, Gliemann J, Andreasen PA. Nykjaer A, et al. J Biol Chem. 1994 Oct 14;269(41):25668-76. J Biol Chem. 1994. PMID: 7929271 Free article.
Pro-uPA bound with lower affinity (EC50 about 10 nM), and efficient binding to alpha 2MR/LRP was dependent on contact with both the A chain and the serine proteinase domain. We analyzed the effect of complex formation with the urokinase receptor since this is the primary t …
Pro-uPA bound with lower affinity (EC50 about 10 nM), and efficient binding to alpha 2MR/LRP was dependent on contact with both the A …
133 results