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Regulation of surface-differentiation molecules by epidermal growth factor, transforming growth factor alpha, and hydrocortisone in human mammary epithelial cells transformed by an activated c-Ha-ras proto-oncogene.
Basolo F, Serra C, Ciardiello F, Fiore L, Russo J, Campani D, Dolei A, Squartini F, Toniolo A. Basolo F, et al. Among authors: ciardiello f. Int J Cancer. 1992 Jun 19;51(4):634-40. doi: 10.1002/ijc.2910510421. Int J Cancer. 1992. PMID: 1601524
8-Chloro-cAMP inhibits transforming growth factor alpha transformation of mammary epithelial cells by restoration of the normal mRNA patterns for cAMP-dependent protein kinase regulatory subunit isoforms which show disruption upon transformation.
Ciardiello F, Tortora G, Kim N, Clair T, Ally S, Salomon DS, Cho-Chung YS. Ciardiello F, et al. J Biol Chem. 1990 Jan 15;265(2):1016-20. J Biol Chem. 1990. PMID: 1688548 Free article.
Such selective modulation of protein kinase isozyme regulatory subunits was also found in the 8-Cl-cAMP-induced inhibition of both transformation and transforming growth factor alpha (TGF alpha) production in Ki-ras-transformed rat kidney fibroblasts (Tortora, G., Ciardiello
Such selective modulation of protein kinase isozyme regulatory subunits was also found in the 8-Cl-cAMP-induced inhibition of both transform …
642 results