Wang W - Search Results

1

Subtle Structural Modifications Spanning from EP4 Antagonism to EP2/EP4 Dual Antagonism: A Novel Class of Thienocyclic-Based Derivatives.

Cheng Z, Zhang Y, Du L, Wang W, Chai X, He M, Zhang H, Wu D, Lu J, Zhang S, Feng B, Yang L, Liu M, Lu W. Cheng Z, et al. Among authors: wang w. J Med Chem. 2025 Jan 23;68(2):1587-1607. doi: 10.1021/acs.jmedchem.4c02241. Epub 2025 Jan 6. J Med Chem. 2025. PMID: 39757828

2

Scaffold Hopping Strategy to Identify Prostanoid EP4 Receptor Antagonists for Cancer Immunotherapy.

Wang W, He J, Yang J, Zhang C, Cheng Z, Zhang Y, Zhang Q, Wang P, Tang S, Wang X, Liu M, Lu W, Zhang HK. Wang W, et al. Among authors: wang x, wang p. J Med Chem. 2022 Jun 9;65(11):7896-7917. doi: 10.1021/acs.jmedchem.2c00448. Epub 2022 May 31. J Med Chem. 2022. PMID: 35640059

3

Discovery of 2H-Indazole-3-carboxamide Derivatives as Novel Potent Prostanoid EP4 Receptor Antagonists for Colorectal Cancer Immunotherapy.

Cheng Z, Wang Y, Zhang Y, Zhang C, Wang M, Wang W, He J, Wang Y, Zhang H, Zhang Q, Ding C, Wu D, Yang L, Liu M, Lu W. Cheng Z, et al. Among authors: wang w, wang y, wang m. J Med Chem. 2023 May 11;66(9):6218-6238. doi: 10.1021/acs.jmedchem.2c02058. Epub 2023 Mar 7. J Med Chem. 2023. PMID: 36880691

4

Probing into the plasma stability and microsomal stability of thiol-based prodrug derivatives: Using IYS-15, an HDAC inhibitor as the model thiol.

Zhu L, Wang W, Li Q, Wang H, Lei X. Zhu L, et al. Among authors: wang h, wang w. Bioorg Med Chem. 2025 Jan 5;119:118064. doi: 10.1016/j.bmc.2025.118064. Online ahead of print. Bioorg Med Chem. 2025. PMID: 39793402

5

Synthesis and cytotoxic activities of beta-carboline amino acid ester conjugates.

Zhao M, Bi L, Wang W, Wang C, Baudy-Floc'h M, Ju J, Peng S. Zhao M, et al. Among authors: wang w, wang c. Bioorg Med Chem. 2006 Oct 15;14(20):6998-7010. doi: 10.1016/j.bmc.2006.06.021. Epub 2006 Jun 27. Bioorg Med Chem. 2006. PMID: 16806943

6

(3S)-N-(L-Aminoacyl)-1,2,3,4-tetrahydroisoquinolines, a class of novel antithrombotic agents: synthesis, bioassay, 3D QSAR, and ADME analysis.

Zheng M, Zhang X, Zhao M, Chang HW, Wang W, Wang Y, Peng S. Zheng M, et al. Among authors: wang w, wang y. Bioorg Med Chem. 2008 Nov 1;16(21):9574-87. doi: 10.1016/j.bmc.2008.09.019. Epub 2008 Sep 12. Bioorg Med Chem. 2008. PMID: 18835178

7

Design, synthesis and biological evaluation of novel dual inhibitors of acetylcholinesterase and beta-secretase.

Zhu Y, Xiao K, Ma L, Xiong B, Fu Y, Yu H, Wang W, Wang X, Hu D, Peng H, Li J, Gong Q, Chai Q, Tang X, Zhang H, Li J, Shen J. Zhu Y, et al. Among authors: wang x, wang w. Bioorg Med Chem. 2009 Feb 15;17(4):1600-13. doi: 10.1016/j.bmc.2008.12.067. Epub 2009 Jan 6. Bioorg Med Chem. 2009. PMID: 19162488

8

Identification of Monosaccharide Derivatives as Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin-3.

Liu C, Jalagam PR, Feng J, Wang W, Raja T, Sura MR, Manepalli RKVLP, Aliphedi BR, Medavarapu S, Nair SK, Muthalagu V, Natesan R, Gupta A, Beno B, Panda M, Ghosh K, Shukla JK, Sale H, Haldar P, Kalidindi N, Shah D, Patel D, Mathur A, Ellsworth BA, Cheng D, Regueiro-Ren A. Liu C, et al. Among authors: wang w. J Med Chem. 2022 Aug 25;65(16):11084-11099. doi: 10.1021/acs.jmedchem.2c00517. Epub 2022 Aug 15. J Med Chem. 2022. PMID: 35969688

9

Cell-active, irreversible covalent inhibitors that selectively target the catalytic lysine of EGFR by using fluorosulfate-based SuFEx chemistry.

Tang G, Wang W, Wang X, Ding K, Ngan SC, Chen JY, Sze SK, Gao L, Yuan P, Lu X, Yao SQ. Tang G, et al. Among authors: wang x, wang w. Eur J Med Chem. 2023 Nov 5;259:115671. doi: 10.1016/j.ejmech.2023.115671. Epub 2023 Jul 21. Eur J Med Chem. 2023. PMID: 37499291

10

Design, synthesis and evaluation of antioxidant and anti-inflammatory activities of novel resveratrol derivatives as potential multifunctional drugs.

Lu JX, Wang W, Zhang QW, Guo ZY, Jin Z, Tang YZ. Lu JX, et al. Among authors: wang w. Eur J Med Chem. 2024 Feb 15;266:116148. doi: 10.1016/j.ejmech.2024.116148. Epub 2024 Jan 13. Eur J Med Chem. 2024. PMID: 38237344

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