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EGFR-V834L combined with L858R mutation reduced afatinib sensitivity and associated to early recurrence in lung cancer.
Terada N, Koba H, Nanjo S, Kimura H, Nishiyama A, Yoneda T, Takeda T, Shirasaki H, Nishi K, Sone T, Yamada T, Takayama K, Shibata K, Matsuoka H, Kita T, Nagata K, Tambo Y, Ohkura N, Hara J, Kasahara K, Kohsaka S, Mano H, Yano S. Terada N, et al. Among authors: mano h. Transl Lung Cancer Res. 2024 Nov 30;13(11):3067-3082. doi: 10.21037/tlcr-24-471. Epub 2024 Nov 28. Transl Lung Cancer Res. 2024. PMID: 39670006 Free PMC article.
Somatic mutations in tumor-infiltrating lymphocytes impact on antitumor immunity.
Mukohara F, Iwata K, Ishino T, Inozume T, Nagasaki J, Ueda Y, Suzawa K, Ueno T, Ikeda H, Kawase K, Saeki Y, Kawashima S, Yamashita K, Kawahara Y, Nakamura Y, Honobe-Tabuchi A, Watanabe H, Dansako H, Kawamura T, Suzuki Y, Honda H, Mano H, Toyooka S, Kawazu M, Togashi Y. Mukohara F, et al. Among authors: mano h. Proc Natl Acad Sci U S A. 2024 Aug 27;121(35):e2320189121. doi: 10.1073/pnas.2320189121. Epub 2024 Aug 21. Proc Natl Acad Sci U S A. 2024. PMID: 39167601
GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway.
Ikeuchi H, Matsuno Y, Kusumoto-Matsuo R, Kojima S, Ueno T, Ikegami M, Kitada R, Sumiyoshi-Okuma H, Kojima Y, Yonemori K, Yatabe Y, Takamochi K, Suzuki K, Yoshioka KI, Mano H, Kohsaka S. Ikeuchi H, et al. Among authors: mano h. Oncogene. 2024 Oct;43(41):3037-3048. doi: 10.1038/s41388-024-03105-1. Epub 2024 Aug 3. Oncogene. 2024. PMID: 39095584
584 results