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Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome.
Matico R, Grauwen K, Chauhan D, Yu X, Abdiaj I, Adhikary S, Adriaensen I, Aranzazu GM, Alcázar J, Bassi M, Brisse E, Cañellas S, Chaudhuri S, Delgado F, Diéguez-Vázquez A, Du Jardin M, Eastham V, Finley M, Jacobs T, Keustermans K, Kuhn R, Llaveria J, Leenaerts J, Linares ML, Martín ML, Martín-Pérez R, Martínez C, Miller R, Muñoz FM, Muratore ME, Nooyens A, Perez-Benito L, Perrier M, Pietrak B, Serré J, Sharma S, Somers M, Suarez J, Tresadern G, Trabanco AA, Van den Bulck D, Van Gool M, Van Hauwermeiren F, Varghese T, Vega JA, Youssef SA, Edwards MJ, Oehlrich D, Van Opdenbosch N. Matico R, et al. Among authors: kuhn r. EMBO Mol Med. 2024 Dec 9. doi: 10.1038/s44321-024-00181-4. Online ahead of print. EMBO Mol Med. 2024. PMID: 39653810 Free article.
Flavivirus NS1-triggered endothelial dysfunction promotes virus dissemination.
Puerta-Guardo H, Biering SB, Castillo-Rojas B, DiBiasio-White MJ, Lo NT, Espinosa DA, Warnes CM, Wang C, Cao T, Glasner DR, Beatty PR, Kuhn RJ, Harris E. Puerta-Guardo H, et al. Among authors: kuhn rj. bioRxiv [Preprint]. 2024 Nov 30:2024.11.29.625931. doi: 10.1101/2024.11.29.625931. bioRxiv. 2024. PMID: 39651279 Free PMC article. Preprint.
Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure.
Lisowski P, Lickfett S, Rybak-Wolf A, Menacho C, Le S, Pentimalli TM, Notopoulou S, Dykstra W, Oehler D, López-Calcerrada S, Mlody B, Otto M, Wu H, Richter Y, Roth P, Anand R, Kulka LAM, Meierhofer D, Glazar P, Legnini I, Telugu NS, Hahn T, Neuendorf N, Miller DC, Böddrich A, Polzin A, Mayatepek E, Diecke S, Olzscha H, Kirstein J, Ugalde C, Petrakis S, Cambridge S, Rajewsky N, Kühn R, Wanker EE, Priller J, Metzger JJ, Prigione A. Lisowski P, et al. Among authors: kuhn r. Nat Commun. 2024 Aug 22;15(1):7027. doi: 10.1038/s41467-024-51216-w. Nat Commun. 2024. PMID: 39174523 Free PMC article.
Latino-Hispanic Unsheltered Homelessness Before and After COVID-19.
Delgado Garcia MA, Chinchilla M, Henwood B, Chien J, Kwack S, Kuhn R. Delgado Garcia MA, et al. Among authors: kuhn r. Am J Public Health. 2024 Jul;114(S6):S510-S514. doi: 10.2105/AJPH.2024.307717. Am J Public Health. 2024. PMID: 39083728 Free PMC article.
1,421 results