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Page 1
TRPV4 stimulates colonic afferents through mucosal release of ATP and glutamate.
Meng MY, Paine LW, Sagnat D, Bello I, Oldroyd S, Javid F, Harper MT, Hockley JRF, St John Smith E, Owens RM, Alric L, Buscail E, Welsh F, Vergnolle N, Bulmer DC. Meng MY, et al. Among authors: hockley jrf. Br J Pharmacol. 2024 Dec 3. doi: 10.1111/bph.17408. Online ahead of print. Br J Pharmacol. 2024. PMID: 39626870
Single-cell RNAseq reveals seven classes of colonic sensory neuron.
Hockley JRF, Taylor TS, Callejo G, Wilbrey AL, Gutteridge A, Bach K, Winchester WJ, Bulmer DC, McMurray G, Smith ESJ. Hockley JRF, et al. Gut. 2019 Apr;68(4):633-644. doi: 10.1136/gutjnl-2017-315631. Epub 2018 Feb 26. Gut. 2019. PMID: 29483303 Free PMC article.
5-oxoETE triggers nociception in constipation-predominant irritable bowel syndrome through MAS-related G protein-coupled receptor D.
Bautzova T, Hockley JRF, Perez-Berezo T, Pujo J, Tranter MM, Desormeaux C, Barbaro MR, Basso L, Le Faouder P, Rolland C, Malapert P, Moqrich A, Eutamene H, Denadai-Souza A, Vergnolle N, Smith ESJ, Hughes DI, Barbara G, Dietrich G, Bulmer DC, Cenac N. Bautzova T, et al. Among authors: hockley jrf. Sci Signal. 2018 Dec 18;11(561):eaal2171. doi: 10.1126/scisignal.aal2171. Sci Signal. 2018. PMID: 30563864 Free PMC article.
The voltage-gated sodium channel NaV 1.9 in visceral pain.
Hockley JR, Winchester WJ, Bulmer DC. Hockley JR, et al. Neurogastroenterol Motil. 2016 Mar;28(3):316-26. doi: 10.1111/nmo.12698. Epub 2015 Oct 14. Neurogastroenterol Motil. 2016. PMID: 26462871 Review.
P2Y Receptors Sensitize Mouse and Human Colonic Nociceptors.
Hockley JR, Tranter MM, McGuire C, Boundouki G, Cibert-Goton V, Thaha MA, Blackshaw LA, Michael GJ, Baker MD, Knowles CH, Winchester WJ, Bulmer DC. Hockley JR, et al. J Neurosci. 2016 Feb 24;36(8):2364-76. doi: 10.1523/JNEUROSCI.3369-15.2016. J Neurosci. 2016. PMID: 26911685 Free PMC article.
21 results