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Page 1
Repurposing of lonafarnib as a treatment for SARS-CoV-2 infection.
Khan M, Irvin P, Park SB, Ivester HM, Ricardo-Lax I, Leek M, Grieshaber A, Jang ES, Coutermarsh-Ott SL, Zhang Q, Maio N, Jiang JK, Li B, Huang W, Wang AQ, Xu X, Hu Z, Zheng W, Ye Y, Rouault T, Rice CM, Allen IC, Liang TJ. Khan M, et al. Among authors: ricardo lax i. JCI Insight. 2024 Dec 3:e182704. doi: 10.1172/jci.insight.182704. Online ahead of print. JCI Insight. 2024. PMID: 39625789 Free article.
Distinct pathways for evolution of enhanced receptor binding and cell entry in SARS-like bat coronaviruses.
Tse AL, Acreman CM, Ricardo-Lax I, Berrigan J, Lasso G, Balogun T, Kearns FL, Casalino L, McClain GL, Chandran AM, Lemeunier C, Amaro RE, Rice CM, Jangra RK, McLellan JS, Chandran K, Miller EH. Tse AL, et al. Among authors: ricardo lax i. PLoS Pathog. 2024 Nov 15;20(11):e1012704. doi: 10.1371/journal.ppat.1012704. eCollection 2024 Nov. PLoS Pathog. 2024. PMID: 39546542 Free PMC article.
A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist.
Le Pen J, Paniccia G, Kinast V, Moncada-Velez M, Ashbrook AW, Bauer M, Hoffmann HH, Pinharanda A, Ricardo-Lax I, Stenzel AF, Rosado-Olivieri EA, Dinnon KH 3rd, Doyle WC, Freije CA, Hong SH, Lee D, Lewy T, Luna JM, Peace A, Schmidt C, Schneider WM, Winkler R, Yip EZ, Larson C, McGinn T, Menezes MR, Ramos-Espiritu L, Banerjee P, Poirier JT, Sànchez-Rivera FJ, Cobat A, Zhang Q, Casanova JL, Carroll TS, Glickman JF, Michailidis E, Razooky B, MacDonald MR, Rice CM. Le Pen J, et al. Among authors: ricardo lax i. PLoS Biol. 2024 Sep 24;22(9):e3002767. doi: 10.1371/journal.pbio.3002767. eCollection 2024 Sep. PLoS Biol. 2024. PMID: 39316623 Free PMC article.
Distinct pathway for evolution of enhanced receptor binding and cell entry in SARS-like bat coronaviruses.
Tse AL, Acreman CM, Ricardo-Lax I, Berrigan J, Lasso G, Balogun T, Kearns FL, Casalino L, McClain GL, Chandran AM, Lemeunier C, Amaro RE, Rice CM, Jangra RK, McLellan JS, Chandran K, Miller EH. Tse AL, et al. Among authors: ricardo lax i. bioRxiv [Preprint]. 2024 Jul 13:2024.06.24.600393. doi: 10.1101/2024.06.24.600393. bioRxiv. 2024. Update in: PLoS Pathog. 2024 Nov 15;20(11):e1012704. doi: 10.1371/journal.ppat.1012704 PMID: 38979151 Free PMC article. Updated. Preprint.
A general method for quantitative fractionation of mammalian cells.
Udi Y, Zhang W, Stein ME, Ricardo-Lax I, Pasolli HA, Chait BT, Rout MP. Udi Y, et al. Among authors: ricardo lax i. J Cell Biol. 2023 Jun 5;222(6):e202209062. doi: 10.1083/jcb.202209062. Epub 2023 Mar 15. J Cell Biol. 2023. PMID: 36920247 Free PMC article.
Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice.
Kabbani M, Michailidis E, Steensels S, Fulmer CG, Luna JM, Le Pen J, Tardelli M, Razooky B, Ricardo-Lax I, Zou C, Zeck B, Stenzel AF, Quirk C, Foquet L, Ashbrook AW, Schneider WM, Belkaya S, Lalazar G, Liang Y, Pittman M, Devisscher L, Suemizu H, Theise ND, Chiriboga L, Cohen DE, Copenhaver R, Grompe M, Meuleman P, Ersoy BA, Rice CM, de Jong YP. Kabbani M, et al. Among authors: ricardo lax i. Cell Rep. 2022 Sep 13;40(11):111321. doi: 10.1016/j.celrep.2022.111321. Cell Rep. 2022. PMID: 36103835 Free PMC article.
RNR-R2 Upregulation by a Short Non-Coding Viral Transcript.
Broennimann K, Ricardo-Lax I, Adler J, Michailidis E, de Jong YP, Reuven N, Shaul Y. Broennimann K, et al. Among authors: ricardo lax i. Biomolecules. 2021 Dec 3;11(12):1822. doi: 10.3390/biom11121822. Biomolecules. 2021. PMID: 34944466 Free PMC article.
Replication and single-cycle delivery of SARS-CoV-2 replicons.
Ricardo-Lax I, Luna JM, Thao TTN, Le Pen J, Yu Y, Hoffmann HH, Schneider WM, Razooky BS, Fernandez-Martinez J, Schmidt F, Weisblum Y, Trüeb BS, Berenguer Veiga I, Schmied K, Ebert N, Michailidis E, Peace A, Sánchez-Rivera FJ, Lowe SW, Rout MP, Hatziioannou T, Bieniasz PD, Poirier JT, MacDonald MR, Thiel V, Rice CM. Ricardo-Lax I, et al. Science. 2021 Nov 26;374(6571):1099-1106. doi: 10.1126/science.abj8430. Epub 2021 Oct 14. Science. 2021. PMID: 34648371 Free PMC article.
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks.
Schneider WM, Luna JM, Hoffmann HH, Sánchez-Rivera FJ, Leal AA, Ashbrook AW, Le Pen J, Ricardo-Lax I, Michailidis E, Peace A, Stenzel AF, Lowe SW, MacDonald MR, Rice CM, Poirier JT. Schneider WM, et al. Among authors: ricardo lax i. Cell. 2021 Jan 7;184(1):120-132.e14. doi: 10.1016/j.cell.2020.12.006. Epub 2020 Dec 9. Cell. 2021. PMID: 33382968 Free PMC article.
20 results