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18 results

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The pyruvate dehydrogenase kinase inhibitor dichloroacetate mitigates alcohol-induced hepatic inflammation and metabolic disturbances in mice.
Wu J, Huang E, McMullen MR, Singh V, Mrdjen M, Bellar A, Wang L, Welch N, Dasarathy J, Dasarathy S, Streem D, Brown JM, Nagy LE. Wu J, et al. Among authors: streem d. Hepatol Commun. 2024 Nov 29;8(12):e0547. doi: 10.1097/HC9.0000000000000547. eCollection 2024 Dec 1. Hepatol Commun. 2024. PMID: 39621302 Free PMC article.
Evidence that extracellular HSPB1 contributes to inflammation in alcohol-associated hepatitis.
Overstreet AC, Burge M, Bellar A, McMullen M, Czarnecki D, Huang E, Pathak V, Finney C, Vij R, Dasarathy S, Dasarathy J, Streem D, Welch N, Rotroff D, Schmitt AM, Nagy LE, Messer JS. Overstreet AC, et al. Among authors: streem d. medRxiv [Preprint]. 2024 Sep 6:2024.09.06.24313193. doi: 10.1101/2024.09.06.24313193. medRxiv. 2024. PMID: 39281760 Free PMC article. Preprint.
Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury.
Varadharajan V, Ramachandiran I, Massey WJ, Jain R, Banerjee R, Horak AJ, McMullen MR, Huang E, Bellar A, Lorkowski SW, Gulshan K, Helsley RN, James I, Pathak V, Dasarathy J, Welch N, Dasarathy S, Streem D, Reizes O, Allende DS, Smith JD, Simcox J, Nagy LE, Brown JM. Varadharajan V, et al. Among authors: streem d. Elife. 2024 Apr 22;12:RP92243. doi: 10.7554/eLife.92243. Elife. 2024. PMID: 38648183 Free PMC article.
Proteomics identifies complement protein signatures in patients with alcohol-associated hepatitis.
Taiwo M, Huang E, Pathak V, Bellar A, Welch N, Dasarathy J, Streem D, McClain CJ, Mitchell MC, Barton BA, Szabo G, Dasarathy S; Alcohol Hepatitis Network (AlcHepNet) Consortium; Schaefer EA, Luther J, Day LZ, Ouyang X, Suyavaran A, Mehal WZ, Jacobs JM, Goodman RP, Rotroff DM, Nagy LE. Taiwo M, et al. Among authors: streem d. JCI Insight. 2024 Apr 4;9(9):e174127. doi: 10.1172/jci.insight.174127. JCI Insight. 2024. PMID: 38573776 Free PMC article.
Infective Endocarditis in Patients Addicted to Injected Opioid Drugs.
Javorski MJ, Rosinski BF, Shah S, Thompson MA, Streem D, Gordon SM, Insler S, Houghtaling PL, Griffin B, Blackstone EH, Unai S, Svensson LG, Pettersson GB, Elgharably H. Javorski MJ, et al. Among authors: streem d. J Am Coll Cardiol. 2024 Feb 27;83(8):811-823. doi: 10.1016/j.jacc.2023.12.016. J Am Coll Cardiol. 2024. PMID: 38383096
Dysregulated meta-organismal metabolism of aromatic amino acids in alcohol-associated liver disease.
Mrdjen M, Huang E, Pathak V, Bellar A, Welch N, Dasarathy J, Streem D, McClain CJ, Mitchell M, Radaeva S, Barton B, Szabo G, Dasarathy S, Wang Z, Hazen SL, Brown JM, Nagy LE. Mrdjen M, et al. Among authors: streem d. Hepatol Commun. 2023 Oct 12;7(11):e0284. doi: 10.1097/HC9.0000000000000284. eCollection 2023 Nov 1. Hepatol Commun. 2023. PMID: 37820283 Free PMC article.
Membrane Bound O-Acyltransferase 7 (MBOAT7) Shapes Lysosomal Lipid Homeostasis and Function to Control Alcohol-Associated Liver Injury.
Varadharajan V, Ramachandiran L, Massey WJ, Jain R, Banerjee R, Horak AJ, McMullen MR, Huang E, Bellar A, Lorkowski SW, Guilshan K, Helsley RN, James I, Pathak V, Dasarathy J, Welch N, Dasarathy S, Streem D, Reizes O, Allende DS, Smith JD, Simcox J, Nagy LE, Brown JM. Varadharajan V, et al. Among authors: streem d. bioRxiv [Preprint]. 2024 Jan 10:2023.09.26.559533. doi: 10.1101/2023.09.26.559533. bioRxiv. 2024. Update in: Elife. 2024 Apr 22;12:RP92243. doi: 10.7554/eLife.92243 PMID: 37808828 Free PMC article. Updated. Preprint.
Altered anti-viral immune responses in monocytes in overweight heavy drinkers.
Kim A, Ortega-Ribera M, McMullen MR, Bellar A, Taiwo M, Pathak V, Streem D, Dasarathy J, Welch N, Dasarathy S, Vachharajani V, Nagy LE. Kim A, et al. Among authors: streem d. iScience. 2023 Jul 21;26(7):107133. doi: 10.1016/j.isci.2023.107133. Epub 2023 Jun 15. iScience. 2023. PMID: 37361874 Free PMC article.
18 results