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A meta-analysis of the effects of early life stress on the prefrontal cortex transcriptome suggests long-term effects on myelin.
Duan TQ, Hagenauer MH, Flandreau EI, Bader A, Nguyen DM, Maras PM, De Lima RMS, Gyles T, Mclain C, Meaney MJ, Nestler EJ, Watson SJ Jr, Akil H. Duan TQ, et al. Among authors: flandreau ei. bioRxiv [Preprint]. 2024 Nov 24:2024.11.22.624315. doi: 10.1101/2024.11.22.624315. bioRxiv. 2024. PMID: 39605735 Free PMC article. Preprint.
Animal Models of PTSD: A Critical Review.
Flandreau EI, Toth M. Flandreau EI, et al. Curr Top Behav Neurosci. 2018;38:47-68. doi: 10.1007/7854_2016_65. Curr Top Behav Neurosci. 2018. PMID: 28070873 Review.
Forebrain-specific CRF overproduction during development is sufficient to induce enduring anxiety and startle abnormalities in adult mice.
Toth M, Gresack JE, Bangasser DA, Plona Z, Valentino RJ, Flandreau EI, Mansuy IM, Merlo-Pich E, Geyer MA, Risbrough VB. Toth M, et al. Among authors: flandreau ei. Neuropsychopharmacology. 2014 May;39(6):1409-19. doi: 10.1038/npp.2013.336. Epub 2013 Dec 11. Neuropsychopharmacology. 2014. PMID: 24326400 Free PMC article.
Chronic overexpression of corticotropin-releasing factor from the central amygdala produces HPA axis hyperactivity and behavioral anxiety associated with gene-expression changes in the hippocampus and paraventricular nucleus of the hypothalamus.
Flandreau EI, Ressler KJ, Owens MJ, Nemeroff CB. Flandreau EI, et al. Psychoneuroendocrinology. 2012 Jan;37(1):27-38. doi: 10.1016/j.psyneuen.2011.04.014. Epub 2011 May 26. Psychoneuroendocrinology. 2012. PMID: 21616602 Free PMC article.