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Page 1
Perspectives on Codebook: sequence specificity of uncharacterized human transcription factors.
Jolma A, Laverty KU, Fathi A, Yang AWH, Yellan I, Vorontsov IE, Inukai S, Kribelbauer-Swietek JF, Gralak AJ, Razavi R, Albu M, Brechalov A, Patel ZM, Nozdrin V, Meshcheryakov G, Kozin I, Abramov S, Boytsov A; Codebook Consortium; Fornes O, Makeev VJ, Grau J, Grosse I, Bucher P, Deplancke B, Kulakovskiy IV, Hughes TR. Jolma A, et al. Among authors: yang awh. bioRxiv [Preprint]. 2024 Nov 12:2024.11.11.622097. doi: 10.1101/2024.11.11.622097. bioRxiv. 2024. PMID: 39605729 Free PMC article. Preprint.
Cross-platform DNA motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors.
Vorontsov IE, Kozin I, Abramov S, Boytsov A, Jolma A, Albu M, Ambrosini G, Faltejskova K, Gralak AJ, Gryzunov N, Inukai S, Kolmykov S, Kravchenko P, Kribelbauer-Swietek JF, Laverty KU, Nozdrin V, Patel ZM, Penzar D, Plescher ML, Pour SE, Razavi R, Yang AWH, Yevshin I, Zinkevich A, Weirauch MT, Bucher P, Deplancke B, Fornes O, Grau J, Grosse I, Kolpakov FA; Codebook/GRECO-BIT Consortium; Makeev VJ, Hughes TR, Kulakovskiy IV. Vorontsov IE, et al. Among authors: yang awh. bioRxiv [Preprint]. 2024 Nov 13:2024.11.11.619379. doi: 10.1101/2024.11.11.619379. bioRxiv. 2024. PMID: 39605530 Free PMC article. Preprint.
Identification of methylation-sensitive human transcription factors using meSMiLE-seq.
Gralak AJ, Faltejskova K, Yang AWH, Steiner C, Russeil J, Grenningloh N, Inukai S, Demir M, Dainese R, Owen C, Pankevich E; Codebook/GRECO-BIT Consortium; Hughes TR, Kulakovskiy IV, Kribelbauer-Swietek JF, van Mierlo G, Deplancke B. Gralak AJ, et al. Among authors: yang awh. bioRxiv [Preprint]. 2024 Nov 12:2024.11.11.619598. doi: 10.1101/2024.11.11.619598. bioRxiv. 2024. PMID: 39605503 Free PMC article. Preprint.
GHT-SELEX demonstrates unexpectedly high intrinsic sequence specificity and complex DNA binding of many human transcription factors.
Jolma A, Hernandez-Corchado A, Yang AWH, Fathi A, Laverty KU, Brechalov A, Razavi R, Albu M, Zheng H; Codebook Consortium; Kulakovskiy IV, Najafabadi HS, Hughes TR. Jolma A, et al. Among authors: yang awh. bioRxiv [Preprint]. 2024 Nov 12:2024.11.11.618478. doi: 10.1101/2024.11.11.618478. bioRxiv. 2024. PMID: 39605368 Free PMC article. Preprint.
Extensive binding of uncharacterized human transcription factors to genomic dark matter.
Razavi R, Fathi A, Yellan I, Brechalov A, Laverty KU, Jolma A, Hernandez-Corchado A, Zheng H, Yang AWH, Albu M, Barazandeh M, Hu C, Vorontsov IE, Patel ZM; Codebook Consortium; Kulakovskiy IV, Bucher P, Morris Q, Najafabadi HS, Hughes TR. Razavi R, et al. Among authors: yang awh. bioRxiv [Preprint]. 2024 Nov 12:2024.11.11.622123. doi: 10.1101/2024.11.11.622123. bioRxiv. 2024. PMID: 39605320 Free PMC article. Preprint.
Identification of inhibitors from a functional food-based plant Perillae Folium against hyperuricemia via metabolomics profiling, network pharmacology and all-atom molecular dynamics simulations.
Wu C, Wong AR, Chen Q, Yang S, Chen M, Sun X, Zhou L, Liu Y, Yang AWH, Bi J, Hung A, Li H, Zhao X. Wu C, et al. Among authors: yang awh. Front Endocrinol (Lausanne). 2024 Feb 16;15:1320092. doi: 10.3389/fendo.2024.1320092. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38435751 Free PMC article.
The human genome contains over a million autonomous exons.
Stepankiw N, Yang AWH, Hughes TR. Stepankiw N, et al. Among authors: yang awh. Genome Res. 2023 Dec 1;33(11):1865-1878. doi: 10.1101/gr.277792.123. Genome Res. 2023. PMID: 37945377 Free PMC article.
56 results