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Exome sequencing in Asian populations identifies low-frequency and rare coding variation influencing Parkinson's disease risk.
Chew EG, Liu Z, Li Z, Chung SJ, Lian MM, Tandiono M, Heng YJ, Ng EY, Tan LC, Chng WL, Tan TJ, Peh EK, Ho YS, Chen XY, Lim EY, Chang CH, Leong JJ, Peh TX, Chan LL, Chao Y, Au WL, Prakash KM, Lim JL, Tay YW, Mok V, Chan AY, Lin JJ, Jeon BS, Song K, Tham CC, Pang CP, Ahn J, Park KH, Wiggs JL, Aung T, Tan AH, Ahmad Annuar A, Makarious MB, Blauwendraat C, Nalls MA, Robak LA, Alcalay RN, Gan-Or Z, Reynolds R, Lim SY, Xia Y, Khor CC, Tan EK, Wang Z, Foo JN. Chew EG, et al. Among authors: lim jl. Nat Aging. 2024 Nov 21. doi: 10.1038/s43587-024-00760-7. Online ahead of print. Nat Aging. 2024. PMID: 39572736
ARGX-119 is an agonist antibody for human MuSK that reverses disease relapse in a mouse model of congenital myasthenic syndrome.
Vanhauwaert R, Oury J, Vankerckhoven B, Steyaert C, Jensen SM, Vergoossen DLE, Kneip C, Santana L, Lim JL, Plomp JJ, Augustinus R, Koide S, Blanchetot C, Ulrichts P, Huijbers MG, Silence K, Burden SJ. Vanhauwaert R, et al. Among authors: lim jl. Sci Transl Med. 2024 Sep 18;16(765):eado7189. doi: 10.1126/scitranslmed.ado7189. Epub 2024 Sep 18. Sci Transl Med. 2024. PMID: 39292800
Ongoing genome doubling promotes evolvability and immune dysregulation in ovarian cancer.
McPherson A, Vázquez-García I, Myers MA, Zatzman M, Al-Rawi D, Weiner A, Freeman S, Mohibullah N, Satas G, Williams MJ, Ceglia N, Zhang AW, Li J, Lim JLP, Wu M, Choi S, Havasov E, Grewal D, Shi H, Kim M, Schwarz R, Kaufmann T, Dinh KN, Uhlitz F, Tran J, Wu Y, Patel R, Ramakrishnan S, Kim D, Clarke J, Green H, Ali E, DiBona M, Varice N, Kundra R, Broach V, Gardner GJ, Roche KL, Sonoda Y, Zivanovic O, Kim SH, Grisham RN, Liu YL, Viale A, Rusk N, Lakhman Y, Ellenson LH, Tavaré S, Aparicio S, Chi DS, Aghajanian C, Abu-Rustum NR, Friedman CF, Zamarin D, Weigelt B, Bakhoum SF, Shah SP. McPherson A, et al. Among authors: lim jlp. bioRxiv [Preprint]. 2024 Jul 15:2024.07.11.602772. doi: 10.1101/2024.07.11.602772. bioRxiv. 2024. PMID: 39071261 Free PMC article. Preprint.
Oral Exposure to Benzalkonium Chlorides in Male and Female Mice Reveals Sex-Dependent Alteration of the Gut Microbiome and Bile Acid Profile.
Lopez VA, Lim JL, Seguin RP, Dempsey JL, Kunzman G, Cui JY, Xu L. Lopez VA, et al. Among authors: lim jl. bioRxiv [Preprint]. 2024 May 16:2024.05.13.593991. doi: 10.1101/2024.05.13.593991. bioRxiv. 2024. Update in: Toxicol Sci. 2024 Oct 03:kfae116. doi: 10.1093/toxsci/kfae116. PMID: 38798482 Free PMC article. Updated. Preprint.
Generation of stable suspension producer cell lines for serum-free lentivirus production.
Klimpel M, Terrao M, Bräuer M, Dersch H, Biserni M, Melo Do Nascimento L, Schwingal S, Vogel JE, Ferlemann C, Brandt T, Lal NI, Bridgeman K, Petzke A, McDwyer E, Lim JL, Oh S, Brumatti G, Garcia Minambres A, Otte E, Noll T, Pirzas V, Laux H. Klimpel M, et al. Among authors: lim jl. Biotechnol J. 2024 May;19(5):e2400090. doi: 10.1002/biot.202400090. Biotechnol J. 2024. PMID: 38719592
120 results