D'Andrea L - Search Results

1

Structure of the human TSC:WIPI3 lysosomal recruitment complex.

Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM. Bayly-Jones C, et al. Among authors: d andrea l. Sci Adv. 2024 Nov 22;10(47):eadr5807. doi: 10.1126/sciadv.adr5807. Epub 2024 Nov 20. Sci Adv. 2024. PMID: 39565846 Free PMC article.

2

The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.

Lupton CJ, Bayly-Jones C, D'Andrea L, Huang C, Schittenhelm RB, Venugopal H, Whisstock JC, Halls ML, Ellisdon AM. Lupton CJ, et al. Nat Struct Mol Biol. 2021 Dec;28(12):982-988. doi: 10.1038/s41594-021-00687-2. Epub 2021 Dec 9. Nat Struct Mol Biol. 2021. PMID: 34887559

3

Structural analysis of the PTEN:P-Rex2 signaling complex reveals how cancer-associated mutations coordinate to hyperactivate Rac1.

D'Andrea L, Lucato CM, Marquez EA, Chang YG, Civciristov S, Mastos C, Lupton CJ, Huang C, Elmlund H, Schittenhelm RB, Mitchell CA, Whisstock JC, Halls ML, Ellisdon AM. D'Andrea L, et al. Sci Signal. 2021 May 4;14(681):eabc4078. doi: 10.1126/scisignal.abc4078. Sci Signal. 2021. PMID: 33947796

4

Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism.

Chang YG, Lupton CJ, Bayly-Jones C, Keen AC, D'Andrea L, Lucato CM, Steele JR, Venugopal H, Schittenhelm RB, Whisstock JC, Halls ML, Ellisdon AM. Chang YG, et al. Nat Struct Mol Biol. 2022 Aug;29(8):767-773. doi: 10.1038/s41594-022-00804-9. Epub 2022 Jul 21. Nat Struct Mol Biol. 2022. PMID: 35864164 Free PMC article.

5

Homodimerization attenuates the anti-inflammatory activity of interleukin-37.

Ellisdon AM, Nold-Petry CA, D'Andrea L, Cho SX, Lao JC, Rudloff I, Ngo D, Lo CY, Soares da Costa TP, Perugini MA, Conroy PJ, Whisstock JC, Nold MF. Ellisdon AM, et al. Sci Immunol. 2017 Feb 10;2(8):eaaj1548. doi: 10.1126/sciimmunol.aaj1548. Sci Immunol. 2017. PMID: 28783685

6

Parsing the IL-37-Mediated Suppression of Inflammasome Function.

Rudloff I, Ung HK, Dowling JK, Mansell A, D'Andrea L, Ellisdon AM, Whisstock JC, Berger PJ, Nold-Petry CA, Nold MF. Rudloff I, et al. Cells. 2020 Jan 10;9(1):178. doi: 10.3390/cells9010178. Cells. 2020. PMID: 31936823 Free PMC article.

7

Protein engineering of a stable and potent anti-inflammatory IL-37-Fc fusion with enhanced therapeutic potential.

Bujotzek A, Tiefenthaler G, Lariviere L, D'Andrea L, Marquez EA, Rudloff I, Cho SX, Deen NS, Richter W, Regenass-Lechner F, Poehler A, Whisstock JC, Sydow-Andersen J, Reiser X, Schuster S, Neubauer J, Hoepfl S, Richter K, Nold MF, Nold-Petry CA, Schumacher F, Ellisdon AM. Bujotzek A, et al. Cell Chem Biol. 2022 Apr 21;29(4):586-596.e4. doi: 10.1016/j.chembiol.2021.10.004. Epub 2021 Oct 25. Cell Chem Biol. 2022. PMID: 34699747 Free article.

8

A molecular switch governs the interaction between the human complement protease C1s and its substrate, complement C4.

Perry AJ, Wijeyewickrema LC, Wilmann PG, Gunzburg MJ, D'Andrea L, Irving JA, Pang SS, Duncan RC, Wilce JA, Whisstock JC, Pike RN. Perry AJ, et al. J Biol Chem. 2013 May 31;288(22):15821-9. doi: 10.1074/jbc.M113.464545. Epub 2013 Apr 16. J Biol Chem. 2013. PMID: 23592783 Free PMC article.

9

A Novel In Silico-Ex Vivo Model for Correlating Coating Transfer to Tissue with Local Drug-Coated Balloon-Vessel Contact Pressures.

Stratakos E, Tscheuschner L, Vincenzi L, Pedrinazzi E, Sigala F, D'Andrea L, Gastaldi D, Berti F, Tzafriri AR, Pennati G. Stratakos E, et al. Among authors: d andrea l. Ann Biomed Eng. 2024 Dec 12. doi: 10.1007/s10439-024-03634-6. Online ahead of print. Ann Biomed Eng. 2024. PMID: 39665865

10

Morphology and Applications of Self-Assembled Peptide Nucleic Acids.

D'Andrea LD, Romanelli A. D'Andrea LD, et al. Int J Mol Sci. 2024 Nov 19;25(22):12435. doi: 10.3390/ijms252212435. Int J Mol Sci. 2024. PMID: 39596501 Free PMC article. Review.

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