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Page 1
Active state structures of a bistable visual opsin bound to G proteins.
Tejero O, Pamula F, Koyanagi M, Nagata T, Afanasyev P, Das I, Deupi X, Sheves M, Terakita A, Schertler GFX, Rodrigues MJ, Tsai CJ. Tejero O, et al. Among authors: deupi x. Nat Commun. 2024 Oct 16;15(1):8928. doi: 10.1038/s41467-024-53208-2. Nat Commun. 2024. PMID: 39414813 Free PMC article.
Ultrafast structural changes direct the first molecular events of vision.
Gruhl T, Weinert T, Rodrigues MJ, Milne CJ, Ortolani G, Nass K, Nango E, Sen S, Johnson PJM, Cirelli C, Furrer A, Mous S, Skopintsev P, James D, Dworkowski F, Båth P, Kekilli D, Ozerov D, Tanaka R, Glover H, Bacellar C, Brünle S, Casadei CM, Diethelm AD, Gashi D, Gotthard G, Guixà-González R, Joti Y, Kabanova V, Knopp G, Lesca E, Ma P, Martiel I, Mühle J, Owada S, Pamula F, Sarabi D, Tejero O, Tsai CJ, Varma N, Wach A, Boutet S, Tono K, Nogly P, Deupi X, Iwata S, Neutze R, Standfuss J, Schertler G, Panneels V. Gruhl T, et al. Among authors: deupi x. Nature. 2023 Mar;615(7954):939-944. doi: 10.1038/s41586-023-05863-6. Epub 2023 Mar 22. Nature. 2023. PMID: 36949205 Free PMC article.
Structural Elements Directing G Proteins and β-Arrestin Interactions with the Human Melatonin Type 2 Receptor Revealed by Natural Variants.
Plouffe B, Karamitri A, Flock T, Gallion JM, Houston S, Daly CA, Bonnefond A, Guillaume JL, Le Gouill C, Froguel P, Lichtarge O, Deupi X, Jockers R, Bouvier M. Plouffe B, et al. Among authors: deupi x. ACS Pharmacol Transl Sci. 2022 Jan 25;5(2):89-101. doi: 10.1021/acsptsci.1c00239. eCollection 2022 Feb 11. ACS Pharmacol Transl Sci. 2022. PMID: 35846981 Free PMC article.
Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants.
Hegron A, Huh E, Deupi X, Sokrat B, Gao W, Le Gouill C, Canouil M, Boissel M, Charpentier G, Roussel R, Balkau B, Froguel P, Plouffe B, Bonnefond A, Lichtarge O, Jockers R, Bouvier M. Hegron A, et al. Among authors: deupi x. ACS Pharmacol Transl Sci. 2021 Sep 1;4(5):1614-1627. doi: 10.1021/acsptsci.1c00157. eCollection 2021 Oct 8. ACS Pharmacol Transl Sci. 2021. PMID: 34661078 Free PMC article.
80 results