Liggett SB - Search Results

1

Agonist activation to open the Gα subunit of the GPCR-G protein precoupled complex defines functional agonist activation of TAS2R5.

Young Yang M, Duy Mac K, Strzelinski HR, Hoffman SA, Kim D, Kim SK, Su J, Liggett SB, Goddard WA 3rd. Young Yang M, et al. Among authors: liggett sb. Proc Natl Acad Sci U S A. 2024 Nov 26;121(48):e2409987121. doi: 10.1073/pnas.2409987121. Epub 2024 Nov 20. Proc Natl Acad Sci U S A. 2024. PMID: 39565310

2

Label-free, real-time monitoring of membrane binding events at zeptomolar concentrations using frequency-locked optical microresonators.

Gin A, Nguyen PD, Melzer JE, Li C, Strzelinski H, Liggett SB, Su J. Gin A, et al. Among authors: liggett sb. Nat Commun. 2024 Aug 28;15(1):7445. doi: 10.1038/s41467-024-51320-x. Nat Commun. 2024. PMID: 39198447 Free PMC article.

3

Author Correction: Activated cofilin exacerbates tau pathology by impairing tau-mediated microtubule dynamics.

Woo JA, Liu T, Fang CC, Cazzaro S, Kee T, LePochat P, Yrigoin K, Penn C, Zhao X, Wang X, Liggett SB, Kang DE. Woo JA, et al. Among authors: liggett sb. Commun Biol. 2023 Dec 19;6(1):1283. doi: 10.1038/s42003-023-05644-x. Commun Biol. 2023. PMID: 38114710 Free PMC article. No abstract available.

4

How carvedilol does not activate β₂-adrenoceptors.

Lefkowitz RJ, Rockman HA, Shim PJ, Liu S, Ahn S, Pani B, Rajagopal S, Shenoy SK, Bouvier M, Benovic JL, Liggett SB, Ruffolo RR, Bristow MR, Packer M. Lefkowitz RJ, et al. Among authors: liggett sb. Nat Commun. 2023 Nov 30;14(1):7866. doi: 10.1038/s41467-023-42848-5. Nat Commun. 2023. PMID: 38036531 Free PMC article. No abstract available.

5

Label-free, real-time monitoring of membrane binding events at zeptomolar concentrations using frequency-locked optical microresonators.

Gin A, Nguyen PD, Melzer JE, Li C, Strzelinski H, Liggett SB, Su J. Gin A, et al. Among authors: liggett sb. bioRxiv [Preprint]. 2023 Sep 22:2023.09.20.558657. doi: 10.1101/2023.09.20.558657. bioRxiv. 2023. Update in: Nat Commun. 2024 Aug 28;15(1):7445. doi: 10.1038/s41467-024-51320-x PMID: 37786702 Free PMC article. Updated. Preprint.

6

An extensive β1-adrenergic receptor gene signaling network regulates molecular remodeling in dilated cardiomyopathies.

Tatman PD, Kao DP, Chatfield KC, Carroll IA, Wagner JA, Jonas ER, Sucharov CC, Port JD, Lowes BD, Minobe WA, Huebler SP, Karimpour-Fard A, Rodriguez EM, Liggett SB, Bristow MR. Tatman PD, et al. Among authors: liggett sb. JCI Insight. 2023 Aug 22;8(16):e169720. doi: 10.1172/jci.insight.169720. JCI Insight. 2023. PMID: 37606047 Free PMC article.

7

Predicted structure and cell signaling of TAS2R14 reveal receptor hyper-flexibility for detecting diverse bitter tastes.

Tokmakova A, Kim D, Guthrie B, Kim SK, Goddard WA 3rd, Liggett SB. Tokmakova A, et al. Among authors: liggett sb. iScience. 2023 Mar 16;26(4):106422. doi: 10.1016/j.isci.2023.106422. eCollection 2023 Apr 21. iScience. 2023. PMID: 37096045 Free PMC article.

8

A Par3/LIM Kinase/Cofilin Pathway Mediates Human Airway Smooth Muscle Relaxation by TAS2R14.

Woo JA, Castaño M, Kee TR, Lee J, Koziol-White CJ, An SS, Kim D, Kang DE, Liggett SB. Woo JA, et al. Among authors: liggett sb. Am J Respir Cell Mol Biol. 2023 Apr;68(4):417-429. doi: 10.1165/rcmb.2022-0303OC. Am J Respir Cell Mol Biol. 2023. PMID: 36662576 Free PMC article.

9

Selective Signal Capture from Multidimensional GPCR Outputs with Biased Agonists: Progress Towards Novel Drug Development.

Kim D, Tokmakova A, Woo JA, An SS, Goddard WA 3rd, Liggett SB. Kim D, et al. Among authors: liggett sb. Mol Diagn Ther. 2022 Jul;26(4):383-396. doi: 10.1007/s40291-022-00592-4. Epub 2022 May 20. Mol Diagn Ther. 2022. PMID: 35595932 Free PMC article. Review.

10

α_1B/D-adrenoceptors regulate chemokine receptor-mediated leukocyte migration via formation of heteromeric receptor complexes.

Enten GA, Gao X, Strzelinski HR, Weche M, Liggett SB, Majetschak M. Enten GA, et al. Among authors: liggett sb. Proc Natl Acad Sci U S A. 2022 May 17;119(20):e2123511119. doi: 10.1073/pnas.2123511119. Epub 2022 May 10. Proc Natl Acad Sci U S A. 2022. PMID: 35537053 Free PMC article.

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