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Tumor cell-derived spermidine promotes a pro-tumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition.
Kay KE, Lee J, Hong ES, Beilis J, Dayal S, Wesley ER, Mitchell S, Wang SZ, Silver DJ, Volovetz J, Johnson S, McGraw M, Grabowski M, Lu T, Freytag L, Narayana VK, Freytag S, Best SA, Whittle JR, Wang Z, Reizes O, Yu JS, Hazen SL, Brown JM, Bayik D, Lathia J. Kay KE, et al. Among authors: hong es. J Clin Invest. 2024 Nov 19:e177824. doi: 10.1172/JCI177824. Online ahead of print. J Clin Invest. 2024. PMID: 39561012 Free article.
Androgen loss weakens anti-tumor immunity and accelerates brain tumor growth.
Lee J, Chung YM, Curtin L, Silver DJ, Hao Y, Li C, Volovetz J, Hong ES, Jarmula J, Wang SZ, Kay KE, Berens M, Nicosia M, Swanson KR, Sharifi N, Lathia JD. Lee J, et al. Among authors: hong es. Res Sq [Preprint]. 2024 Mar 29:rs.3.rs-4014556. doi: 10.21203/rs.3.rs-4014556/v1. Res Sq. 2024. PMID: 38585839 Free PMC article. Preprint.
miR-644a is a tumor cell-intrinsic mediator of sex bias in glioblastoma.
Hong ES, Wang SZ, Ponti AK, Hajdari N, Lee J, Mulkearns-Hubert EE, Volovetz J, Kay KE, Lathia JD, Dhawan A. Hong ES, et al. bioRxiv [Preprint]. 2024 Mar 12:2024.03.11.584443. doi: 10.1101/2024.03.11.584443. bioRxiv. 2024. PMID: 38559056 Free PMC article. Preprint.
Homeostatic iron regulatory protein drives glioblastoma growth via tumor cell-intrinsic and sex-specific responses.
Troike KM, Wang SZ, Silver DJ, Lee J, Mulkearns-Hubert EE, Hajdari N, Ghosh PK, Kay KE, Beilis JL, Mitchell SE, Bishop CW, Hong ES, Artomov M, Hubert CG, Rajappa P, Connor JR, Fox PL, Kristensen BW, Lathia JD. Troike KM, et al. Among authors: hong es. Neurooncol Adv. 2023 Nov 28;6(1):vdad154. doi: 10.1093/noajnl/vdad154. eCollection 2024 Jan-Dec. Neurooncol Adv. 2023. PMID: 38239626 Free PMC article.
Tumor cell-derived spermidine promotes a pro-tumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition.
Kay KE, Lee J, Hong ES, Beilis J, Dayal S, Wesley E, Mitchell S, Wang SZ, Silver DJ, Volovetz J, Johnson S, McGraw M, Grabowski MM, Lu T, Freytag L, Narayana V, Freytag S, Best SA, Whittle JR, Wang Z, Reizes O, Yu JS, Hazen SL, Brown JM, Bayik D, Lathia JD. Kay KE, et al. Among authors: hong es. bioRxiv [Preprint]. 2023 Nov 16:2023.11.14.567048. doi: 10.1101/2023.11.14.567048. bioRxiv. 2023. PMID: 38014234 Free PMC article. Preprint.
Sex-Biased T-cell Exhaustion Drives Differential Immune Responses in Glioblastoma.
Lee J, Nicosia M, Hong ES, Silver DJ, Li C, Bayik D, Watson DC, Lauko A, Kay KE, Wang SZ, Johnson S, McGraw M, Grabowski MM, Kish DD, Desai AB, Goodman WA, Cameron SJ, Okada H, Valujskikh A, Fairchild RL, Ahluwalia MS, Lathia JD. Lee J, et al. Among authors: hong es. Cancer Discov. 2023 Sep 6;13(9):2090-2105. doi: 10.1158/2159-8290.CD-22-0869. Cancer Discov. 2023. PMID: 37378557 Free PMC article.
79 results