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Page 1
Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prostate cancer in mice.
Morel KL, Germán B, Hamid AA, Nanda JS, Linder S, Bergman AM, van der Poel H, Hofland I, Bekers EM, Trostel SY, Burkhart DL, Wilkinson S, Ku AT, Kim M, Kim J, Ma D, Plummer JT, You S, Su XA, Zwart W, Sowalsky AG, Sweeney CJ, Ellis L. Morel KL, et al. Among authors: burkhart dl. J Clin Invest. 2024 Nov 19:e175680. doi: 10.1172/JCI175680. Online ahead of print. J Clin Invest. 2024. PMID: 39560993 Free article.
MYBL2 Drives Prostate Cancer Plasticity: Inhibiting Its Transcriptional Target CDK2 for RB1-Deficient Neuroendocrine Prostate Cancer.
German B, Alaiwi SA, Ho KL, Nanda JS, Fonseca MA, Burkhart DL, Sheahan AV, Bergom HE, Morel KL, Beltran H, Hwang JH, Freedman ML, Lawrenson K, Ellis L. German B, et al. Among authors: burkhart dl. Cancer Res Commun. 2024 Sep 1;4(9):2295-2307. doi: 10.1158/2767-9764.CRC-24-0069. Cancer Res Commun. 2024. PMID: 39113611 Free PMC article.
In vivo imaging using surface enhanced spatially offset raman spectroscopy (SESORS): balancing sampling frequency to improve overall image acquisition.
Nicolson F, Andreiuk B, Lee E, O'Donnell B, Whitley A, Riepl N, Burkhart DL, Cameron A, Protti A, Rudder S, Yang J, Mabbott S, Haigis KM. Nicolson F, et al. Among authors: burkhart dl. Npj Imaging. 2024;2(1):7. doi: 10.1038/s44303-024-00011-9. Epub 2024 Apr 3. Npj Imaging. 2024. PMID: 38939049 Free PMC article.
Prostate lineage-specific metabolism governs luminal differentiation and response to antiandrogen treatment.
Giafaglione JM, Crowell PD, Delcourt AML, Hashimoto T, Ha SM, Atmakuri A, Nunley NM, Dang RMA, Tian M, Diaz JA, Tika E, Payne MC, Burkhart DL, Li D, Navone NM, Corey E, Nelson PS, Lin NYC, Blanpain C, Ellis L, Boutros PC, Goldstein AS. Giafaglione JM, et al. Among authors: burkhart dl. Nat Cell Biol. 2023 Dec;25(12):1821-1832. doi: 10.1038/s41556-023-01274-x. Epub 2023 Dec 4. Nat Cell Biol. 2023. PMID: 38049604 Free PMC article.
EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer.
Morel KL, Sheahan AV, Burkhart DL, Baca SC, Boufaied N, Liu Y, Qiu X, Cañadas I, Roehle K, Heckler M, Calagua C, Ye H, Pantelidou C, Galbo P, Panja S, Mitrofanova A, Wilkinson S, Whitlock NC, Trostel SY, Hamid AA, Kibel AS, Barbie DA, Choudhury AD, Pomerantz MM, Sweeney CJ, Long HW, Einstein DJ, Shapiro GI, Dougan SK, Sowalsky AG, He HH, Freedman ML, Balk SP, Loda M, Labbé DP, Olson BM, Ellis L. Morel KL, et al. Among authors: burkhart dl. Nat Cancer. 2021 Apr;2(4):444-456. doi: 10.1038/s43018-021-00185-w. Epub 2021 Mar 22. Nat Cancer. 2021. PMID: 33899001 Free PMC article.
Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity.
Bywater MJ, Burkhart DL, Straube J, Sabò A, Pendino V, Hudson JE, Quaife-Ryan GA, Porrello ER, Rae J, Parton RG, Kress TR, Amati B, Littlewood TD, Evan GI, Wilson CH. Bywater MJ, et al. Among authors: burkhart dl. Nat Commun. 2020 Apr 14;11(1):1827. doi: 10.1038/s41467-020-15552-x. Nat Commun. 2020. PMID: 32286286 Free PMC article.
20 results