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Disruption of the autism-associated Pcdh9 gene leads to transcriptional alterations, synapse overgrowth, and defective network activity in the CA1.
Miozzo F, Murru L, Maiellano G, di Iasio I, Zippo AG, Zambrano Avendano A, Metodieva VD, Riccardi S, D'Aliberti D, Spinelli S, Canu T, Chaabane L, Hirano S, Kas MJH, Francolini M, Piazza R, Moretto E, Passafaro M. Miozzo F, et al. Among authors: canu t. J Neurosci. 2024 Nov 18:e0491242024. doi: 10.1523/JNEUROSCI.0491-24.2024. Online ahead of print. J Neurosci. 2024. PMID: 39557582
Establishment of a Transplantation Model of PDAC-Derived Liver Metastases.
Ferrara B, Dugnani E, Citro A, Schiavo Lena M, Marra P, Camisa PR, Policardi M, Canu T, Esposito A, Doglioni C, Piemonti L. Ferrara B, et al. Among authors: canu t. Ann Surg Oncol. 2024 Sep;31(9):6138-6146. doi: 10.1245/s10434-024-15514-3. Epub 2024 Jun 13. Ann Surg Oncol. 2024. PMID: 38869763 Free PMC article.
Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression.
Clerici S, Podrini C, Stefanoni D, Distefano G, Cassina L, Steidl ME, Tronci L, Canu T, Chiaravalli M, Spies D, Bell TA 3rd, Costa AS, Esposito A, D'Alessandro A, Frezza C, Bachi A, Boletta A. Clerici S, et al. Among authors: canu t. EMBO Mol Med. 2024 Jun;16(6):1379-1403. doi: 10.1038/s44321-024-00071-9. Epub 2024 Apr 29. EMBO Mol Med. 2024. PMID: 38684863 Free PMC article.
In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases.
Kerzel T, Giacca G, Beretta S, Bresesti C, Notaro M, Scotti GM, Balestrieri C, Canu T, Redegalli M, Pedica F, Genua M, Ostuni R, Kajaste-Rudnitski A, Oshima M, Tonon G, Merelli I, Aldrighetti L, Dellabona P, Coltella N, Doglioni C, Rancoita PMV, Sanvito F, Naldini L, Squadrito ML. Kerzel T, et al. Among authors: canu t. Cancer Cell. 2023 Nov 13;41(11):1892-1910.e10. doi: 10.1016/j.ccell.2023.09.014. Epub 2023 Oct 19. Cancer Cell. 2023. PMID: 37863068 Free article.
Gold nanorods assisted photothermal therapy of bladder cancer in mice: A computational study on the effects of gold nanorods distribution at the centre, periphery, and surface of bladder cancer.
Cheong JK, Ooi EH, Chiew YS, Menichetti L, Armanetti P, Franchini MC, Alchera E, Locatelli I, Canu T, Maturi M, Popov V, Alfano M. Cheong JK, et al. Among authors: canu t. Comput Methods Programs Biomed. 2023 Mar;230:107363. doi: 10.1016/j.cmpb.2023.107363. Epub 2023 Jan 21. Comput Methods Programs Biomed. 2023. PMID: 36720181 Free article.
Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models.
Birocchi F, Cusimano M, Rossari F, Beretta S, Rancoita PMV, Ranghetti A, Colombo S, Costa B, Angel P, Sanvito F, Callea M, Norata R, Chaabane L, Canu T, Spinelli A, Genua M, Ostuni R, Merelli I, Coltella N, Naldini L. Birocchi F, et al. Among authors: canu t. Sci Transl Med. 2022 Jul 13;14(653):eabl4106. doi: 10.1126/scitranslmed.abl4106. Epub 2022 Jul 13. Sci Transl Med. 2022. PMID: 35857642
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