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Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis.
Zhang G, Panigrahy D, Mahakian LM, Yang J, Liu JY, Stephen Lee KS, Wettersten HI, Ulu A, Hu X, Tam S, Hwang SH, Ingham ES, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. Zhang G, et al. Among authors: liu jy. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6530-5. doi: 10.1073/pnas.1304321110. Epub 2013 Apr 3. Proc Natl Acad Sci U S A. 2013. PMID: 23553837 Free PMC article.
Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis.
Zhang G, Panigrahy D, Hwang SH, Yang J, Mahakian LM, Wettersten HI, Liu JY, Wang Y, Ingham ES, Tam S, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. Zhang G, et al. Among authors: liu jy. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11127-32. doi: 10.1073/pnas.1410432111. Epub 2014 Jul 14. Proc Natl Acad Sci U S A. 2014. PMID: 25024195 Free PMC article.
Lipidomic profiling reveals soluble epoxide hydrolase as a therapeutic target of obesity-induced colonic inflammation.
Wang W, Yang J, Zhang J, Wang Y, Hwang SH, Qi W, Wan D, Kim D, Sun J, Sanidad KZ, Yang H, Park Y, Liu JY, Zhao X, Zheng X, Liu Z, Hammock BD, Zhang G. Wang W, et al. Among authors: liu z, liu jy. Proc Natl Acad Sci U S A. 2018 May 15;115(20):5283-5288. doi: 10.1073/pnas.1721711115. Epub 2018 May 1. Proc Natl Acad Sci U S A. 2018. PMID: 29717038 Free PMC article.
Orally bioavailable potent soluble epoxide hydrolase inhibitors.
Hwang SH, Tsai HJ, Liu JY, Morisseau C, Hammock BD. Hwang SH, et al. Among authors: liu jy. J Med Chem. 2007 Aug 9;50(16):3825-40. doi: 10.1021/jm070270t. Epub 2007 Jul 6. J Med Chem. 2007. PMID: 17616115 Free PMC article.
3,004 results