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Effects of sacubitril/valsartan according to background beta-blocker therapy in patients with heart failure and reduced ejection fraction: Insights from PARADIGM-HF.
Gupta SD, Butt JH, McMurray EGM, Talebi A, Matsumoto S, Rizkala AR, Henderson AD, Desai AS, Lefkowitz M, Packer M, Rouleau JL, Solomon SD, Swedberg K, Zile MR, Jhund PS, McMurray JJV; PARADIGM‐HF Investigators and Committees. Gupta SD, et al. Among authors: packer m. Eur J Heart Fail. 2024 Nov 19. doi: 10.1002/ejhf.3515. Online ahead of print. Eur J Heart Fail. 2024. PMID: 39563094
Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity.
Packer M, Zile MR, Kramer CM, Baum SJ, Litwin SE, Menon V, Ge J, Weerakkody GJ, Ou Y, Bunck MC, Hurt KC, Murakami M, Borlaug BA; SUMMIT Trial Study Group. Packer M, et al. N Engl J Med. 2024 Nov 16. doi: 10.1056/NEJMoa2410027. Online ahead of print. N Engl J Med. 2024. PMID: 39555826
Base-editing corrects metabolic abnormalities in a humanized mouse model for glycogen storage disease type-Ia.
Arnaoutova I, Aratyn-Schaus Y, Zhang L, Packer MS, Chen HD, Lee C, Gautam S, Gregoire FM, Leboeuf D, Boule S, Fernandez TP, Huang V, Cheng LI, Lung G, Bannister B, Decker J, Leete T, Shuang LS, Bock C, Kothiyal P, Grayson P, Mok KW, Quinn JJ, Young L, Barrera L, Ciaramella G, Mansfield BC, Chou JY. Arnaoutova I, et al. Among authors: packer ms. Nat Commun. 2024 Nov 10;15(1):9729. doi: 10.1038/s41467-024-54108-1. Nat Commun. 2024. PMID: 39523369 Free PMC article.
Centrally adjudicated vs. investigator-reported outcomes in randomized heart failure trials.
Wandel S, Desai AS, Chen CW, McMurray JJV, Packer M, Solomon SD, Pfeffer MA, Felker GM, Zannad F, Petrie MC, Jhund PS, Attari Z, Mueller-Velten G, Lefkowitz M, Soergel D, Gimpelewicz C. Wandel S, et al. Among authors: packer m. Eur Heart J. 2024 Nov 9:ehae753. doi: 10.1093/eurheartj/ehae753. Online ahead of print. Eur Heart J. 2024. PMID: 39515836
Uric Acid and SGLT2 Inhibition With Empagliflozin in Heart Failure With Preserved Ejection Fraction: The EMPEROR-Preserved Trial.
Doehner W, Anker SD, Butler J, Zannad F, Filippatos G, Coats AJS, Ferreira JP, Henrichmoeller I, Brueckmann M, Schueler E, Pocock SJ, Januzzi JL, Packer M. Doehner W, et al. Among authors: packer m. JACC Heart Fail. 2024 Oct 9:S2213-1779(24)00626-7. doi: 10.1016/j.jchf.2024.08.020. Online ahead of print. JACC Heart Fail. 2024. PMID: 39453357 Free article.
1,084 results