Nomura T - Search Results

1

Levetiracetam prevents Aβ₄₂ production through SV2a-dependent modulation of App processing in Alzheimer's disease models.

Rao NR, DeGulis O, Nomura T, Lee S, Hark TJ, Dynes JC, Dexter EX, Dulewicz M, Ge J, Upadhyay A, Fornasiero EF, Vassar R, Hanrieder J, Contractor A, Savas JN. Rao NR, et al. Among authors: nomura t. bioRxiv [Preprint]. 2024 Oct 28:2024.10.28.620698. doi: 10.1101/2024.10.28.620698. bioRxiv. 2024. PMID: 39554163 Free PMC article. Preprint.

2

Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer's Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals.

Hark TJ, Rao NR, Castillon C, Basta T, Smukowski S, Bao H, Upadhyay A, Bomba-Warczak E, Nomura T, O'Toole ET, Morgan GP, Ali L, Saito T, Guillermier C, Saido TC, Steinhauser ML, Stowell MHB, Chapman ER, Contractor A, Savas JN. Hark TJ, et al. Among authors: nomura t. Cell Syst. 2021 Feb 17;12(2):141-158.e9. doi: 10.1016/j.cels.2020.11.007. Epub 2020 Dec 15. Cell Syst. 2021. PMID: 33326751 Free PMC article.

3

Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice.

Ou-Yang MH, Kurz JE, Nomura T, Popovic J, Rajapaksha TW, Dong H, Contractor A, Chetkovich DM, Tourtellotte WG, Vassar R. Ou-Yang MH, et al. Among authors: nomura t. Sci Transl Med. 2018 Sep 19;10(459):eaao5620. doi: 10.1126/scitranslmed.aao5620. Sci Transl Med. 2018. PMID: 30232227 Free PMC article.

4

A Pathogenic Missense Mutation in Kainate Receptors Elevates Dendritic Excitability and Synaptic Integration through Dysregulation of SK Channels.

Nomura T, Taniguchi S, Wang YZ, Yeh NH, Wilen AP, Castillon CCM, Foote KM, Xu J, Armstrong JN, Savas JN, Swanson GT, Contractor A. Nomura T, et al. J Neurosci. 2023 Nov 22;43(47):7913-7928. doi: 10.1523/JNEUROSCI.1259-23.2023. J Neurosci. 2023. PMID: 37802657 Free PMC article.

5

Potentiating α₂ subunit containing perisomatic GABA_A receptors protects against seizures in a mouse model of Dravet syndrome.

Nomura T, Hawkins NA, Kearney JA, George AL Jr, Contractor A. Nomura T, et al. J Physiol. 2019 Aug;597(16):4293-4307. doi: 10.1113/JP277651. Epub 2019 May 20. J Physiol. 2019. PMID: 31045243 Free PMC article.

6

The developmental switch in GABA polarity is delayed in fragile X mice.

He Q, Nomura T, Xu J, Contractor A. He Q, et al. Among authors: nomura t. J Neurosci. 2014 Jan 8;34(2):446-50. doi: 10.1523/JNEUROSCI.4447-13.2014. J Neurosci. 2014. PMID: 24403144 Free PMC article.

7

Epac2 Mediates cAMP-Dependent Potentiation of Neurotransmission in the Hippocampus.

Fernandes HB, Riordan S, Nomura T, Remmers CL, Kraniotis S, Marshall JJ, Kukreja L, Vassar R, Contractor A. Fernandes HB, et al. Among authors: nomura t. J Neurosci. 2015 Apr 22;35(16):6544-53. doi: 10.1523/JNEUROSCI.0314-14.2015. J Neurosci. 2015. PMID: 25904804 Free PMC article.

8

Genetic disruption of Grm5 causes complex alterations in motor activity, anxiety and social behaviors.

Xu J, Marshall JJ, Kraniotis S, Nomura T, Zhu Y, Contractor A. Xu J, et al. Among authors: nomura t. Behav Brain Res. 2021 Aug 6;411:113378. doi: 10.1016/j.bbr.2021.113378. Epub 2021 May 21. Behav Brain Res. 2021. PMID: 34029630 Free PMC article.

9

Subchronic phencyclidine treatment in adult mice increases GABAergic transmission and LTP threshold in the hippocampus.

Nomura T, Oyamada Y, Fernandes HB, Remmers CL, Xu J, Meltzer HY, Contractor A. Nomura T, et al. Neuropharmacology. 2016 Jan;100:90-7. doi: 10.1016/j.neuropharm.2015.04.012. Epub 2015 Apr 30. Neuropharmacology. 2016. PMID: 25937215 Free PMC article.

10

Potentiating mGluR5 function with a positive allosteric modulator enhances adaptive learning.

Xu J, Zhu Y, Kraniotis S, He Q, Marshall JJ, Nomura T, Stauffer SR, Lindsley CW, Conn PJ, Contractor A. Xu J, et al. Among authors: nomura t. Learn Mem. 2013 Jul 18;20(8):438-45. doi: 10.1101/lm.031666.113. Learn Mem. 2013. PMID: 23869026 Free PMC article.

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