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Page 1
Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy.
Prieto-Garcia C, Matkovic V, Mosler T, Li C, Liang J, Oo JA, Haidle F, Mačinković I, Cabrera-Orefice A, Berkane R, Giuliani G, Xu F, Jacomin AC, Tomaskovic I, Basoglu M, Hoffmann ME, Rathore R, Cetin R, Boutguetait D, Bozkurt S, Hernández Cañás MC, Keller M, Busam J, Shah VJ, Wittig I, Kaulich M, Beli P, Galej WP, Ebersberger I, Wang L, Münch C, Stolz A, Brandes RP, Tse WKF, Eimer S, Stainier DYR, Legewie S, Zarnack K, Müller-McNicoll M, Dikic I. Prieto-Garcia C, et al. Among authors: shah vj. Science. 2024 Nov 15;386(6723):768-776. doi: 10.1126/science.adi5295. Epub 2024 Nov 14. Science. 2024. PMID: 39541449
Minimized combinatorial CRISPR screens identify genetic interactions in autophagy.
Diehl V, Wegner M, Grumati P, Husnjak K, Schaubeck S, Gubas A, Shah VJ, Polat IH, Langschied F, Prieto-Garcia C, Müller K, Kalousi A, Ebersberger I, Brandts CH, Dikic I, Kaulich M. Diehl V, et al. Among authors: shah vj. Nucleic Acids Res. 2021 Jun 4;49(10):5684-5704. doi: 10.1093/nar/gkab309. Nucleic Acids Res. 2021. PMID: 33956155 Free PMC article.
An engineered cereblon optimized for high throughput screening and molecular glue discovery.
Bailey HJ, Eisert J, Kazi R, Gerhartz J, Pieńkowska DE, Dressel I, Vollrath J, Kondratov I, Matviyuk T, Tolmachova N, Shah VJ, Giuliani G, Mosler T, Geiger TM, Esteves AM, Santos SP, Sousa RL, Bandeiras TM, Leibrock EM, Bauer U, Leuthner B, Langer JD, Wegener AA, Nowak RP, Sorrell FJ, Dikic I. Bailey HJ, et al. Among authors: shah vj. Cell Chem Biol. 2024 Nov 20:S2451-9456(24)00460-4. doi: 10.1016/j.chembiol.2024.11.002. Online ahead of print. Cell Chem Biol. 2024. PMID: 39610248
Relationship between updated MELD and prognosis in alcohol-associated hepatitis: Opportunities for more efficient trial design.
Al-Karaghouli M, Ventura-Cots M, Wong YJ, Genesca J, Bosques F, Brown RS Jr, Mathurin P, Louvet A, Shawcross D, Vargas V, Verna EC, Schnabl B, Caballeria J, Shah VJ, Kamath PS, Lucey MR, Garcia-Tsao G, Bataller R, Abraldes JG. Al-Karaghouli M, et al. Among authors: shah vj. Hepatol Commun. 2024 Jul 31;8(8):e0495. doi: 10.1097/HC9.0000000000000495. eCollection 2024 Aug 1. Hepatol Commun. 2024. PMID: 39082963 Free article.
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