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Page 1
Sequence modeling and design from molecular to genome scale with Evo.
Nguyen E, Poli M, Durrant MG, Kang B, Katrekar D, Li DB, Bartie LJ, Thomas AW, King SH, Brixi G, Sullivan J, Ng MY, Lewis A, Lou A, Ermon S, Baccus SA, Hernandez-Boussard T, Ré C, Hsu PD, Hie BL. Nguyen E, et al. Among authors: durrant mg. Science. 2024 Nov 15;386(6723):eado9336. doi: 10.1126/science.ado9336. Epub 2024 Nov 15. Science. 2024. PMID: 39541441
Bridge RNAs direct programmable recombination of target and donor DNA.
Durrant MG, Perry NT, Pai JJ, Jangid AR, Athukoralage JS, Hiraizumi M, McSpedon JP, Pawluk A, Nishimasu H, Konermann S, Hsu PD. Durrant MG, et al. Nature. 2024 Jun;630(8018):984-993. doi: 10.1038/s41586-024-07552-4. Epub 2024 Jun 26. Nature. 2024. PMID: 38926615 Free PMC article.
Structural mechanism of bridge RNA-guided recombination.
Hiraizumi M, Perry NT, Durrant MG, Soma T, Nagahata N, Okazaki S, Athukoralage JS, Isayama Y, Pai JJ, Pawluk A, Konermann S, Yamashita K, Hsu PD, Nishimasu H. Hiraizumi M, et al. Among authors: durrant mg. Nature. 2024 Jun;630(8018):994-1002. doi: 10.1038/s41586-024-07570-2. Epub 2024 Jun 26. Nature. 2024. PMID: 38926616 Free PMC article.
Bridge RNAs direct modular and programmable recombination of target and donor DNA.
Durrant MG, Perry NT, Pai JJ, Jangid AR, Athukoralage JS, Hiraizumi M, McSpedon JP, Pawluk A, Nishimasu H, Konermann S, Hsu PD. Durrant MG, et al. bioRxiv [Preprint]. 2024 Jan 26:2024.01.24.577089. doi: 10.1101/2024.01.24.577089. bioRxiv. 2024. Update in: Nature. 2024 Jun;630(8018):984-993. doi: 10.1038/s41586-024-07552-4 PMID: 38328150 Free PMC article. Updated. Preprint.
Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting.
Wei J, Lotfy P, Faizi K, Baungaard S, Gibson E, Wang E, Slabodkin H, Kinnaman E, Chandrasekaran S, Kitano H, Durrant MG, Duffy CV, Pawluk A, Hsu PD, Konermann S. Wei J, et al. Among authors: durrant mg. Cell Syst. 2023 Dec 20;14(12):1087-1102.e13. doi: 10.1016/j.cels.2023.11.006. Epub 2023 Dec 12. Cell Syst. 2023. PMID: 38091991
Integration of rare expression outlier-associated variants improves polygenic risk prediction.
Smail C, Ferraro NM, Hui Q, Durrant MG, Aguirre M, Tanigawa Y, Keever-Keigher MR, Rao AS, Justesen JM, Li X, Gloudemans MJ, Assimes TL, Kooperberg C, Reiner AP, Huang J, O'Donnell CJ, Sun YV; Million Veteran Program; Rivas MA, Montgomery SB. Smail C, et al. Among authors: durrant mg. Am J Hum Genet. 2022 Jun 2;109(6):1055-1064. doi: 10.1016/j.ajhg.2022.04.015. Epub 2022 May 18. Am J Hum Genet. 2022. PMID: 35588732 Free PMC article.
15 results