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Covalent Modification of p53 by (E)-1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one.
Brown K, Robello M, Perciaccante AJ, Dinan JC, Maity TK, Lyons GC, Kumar JP, Durell SR, Tagad HD, Schilling D, Nikolayevskiy H, O'Connor R, Appella E, Appella DH, Jenkins LM. Brown K, et al. Among authors: appella e. ACS Pharmacol Transl Sci. 2024 Oct 14;7(11):3559-3572. doi: 10.1021/acsptsci.4c00447. eCollection 2024 Nov 8. ACS Pharmacol Transl Sci. 2024. PMID: 39539265
Publisher Correction: Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques.
Rahman MA, Bissa M, Silva de Castro I, Helmold Hait S, Stamos JD, Bhuyan F, Hunegnaw R, Sarkis S, Gutowska A, Doster MN, Moles R, Hoang T, Miller Jenkins LM, Appella E, Venzon DJ, Choo-Wosoba H, Cardozo T, Baum MM, Appella DH, Robert-Guroff M, Franchini G. Rahman MA, et al. Among authors: appella e. Nat Microbiol. 2023 Aug;8(8):1600. doi: 10.1038/s41564-023-01412-z. Nat Microbiol. 2023. PMID: 37217721 Free PMC article. No abstract available.
Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques.
Rahman MA, Bissa M, Silva de Castro I, Helmold Hait S, Stamos JD, Bhuyan F, Hunegnaw R, Sarkis S, Gutowska A, Doster MN, Moles R, Hoang T, Miller Jenkins LM, Appella E, Venzon DJ, Choo-Wosoba H, Cardozo T, Baum MM, Appella DH, Robert-Guroff M, Franchini G. Rahman MA, et al. Among authors: appella e. Nat Microbiol. 2023 May;8(5):905-918. doi: 10.1038/s41564-023-01353-7. Epub 2023 Apr 6. Nat Microbiol. 2023. PMID: 37024617 Free PMC article.
Discovery of Novel Small-Molecule Scaffolds for the Inhibition and Activation of WIP1 Phosphatase from a RapidFire Mass Spectrometry High-Throughput Screen.
Clausse V, Fang Y, Tao D, Tagad HD, Sun H, Wang Y, Karavadhi S, Lane K, Shi ZD, Vasalatiy O, LeClair CA, Eells R, Shen M, Patnaik S, Appella E, Coussens NP, Hall MD, Appella DH. Clausse V, et al. Among authors: appella e. ACS Pharmacol Transl Sci. 2022 Sep 28;5(10):993-1006. doi: 10.1021/acsptsci.2c00147. eCollection 2022 Oct 14. ACS Pharmacol Transl Sci. 2022. PMID: 36268125 Free PMC article.
Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses.
Uyanik B, Goloudina AR, Akbarali A, Grigorash BB, Petukhov AV, Singhal S, Eruslanov E, Chaloyard J, Lagorgette L, Hadi T, Baidyuk EV, Sakai H, Tessarollo L, Ryffel B, Mazur SJ, Lirussi F, Garrido C, Appella E, Demidov ON. Uyanik B, et al. Among authors: appella e. Nat Commun. 2021 Jun 15;12(1):3622. doi: 10.1038/s41467-021-23330-6. Nat Commun. 2021. PMID: 34131120 Free PMC article.
An SAMT-247 Microbicide Provides Potent Protection against Intravaginal Simian Immunodeficiency Virus Infection of Rhesus Macaques, whereas an Added Vaccine Component Elicits Mixed Outcomes.
Helmold Hait S, Hogge CJ, Rahman MA, Ko EJ, Hunegnaw R, Mushtaq Z, Enyindah-Asonye G, Hoang T, Miller Jenkins LM, Appella E, Appella DH, Robert-Guroff M. Helmold Hait S, et al. Among authors: appella e. J Immunol. 2020 Jun 15;204(12):3315-3328. doi: 10.4049/jimmunol.2000165. Epub 2020 May 11. J Immunol. 2020. PMID: 32393514 Free PMC article.
567 results