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Tumor cell-derived spermidine promotes a pro-tumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition.
Kay KE, Lee J, Hong ES, Beilis J, Dayal S, Wesley ER, Mitchell S, Wang SZ, Silver DJ, Volovetz J, Johnson S, McGraw M, Grabowski M, Lu T, Freytag L, Narayana VK, Freytag S, Best SA, Whittle JR, Wang Z, Reizes O, Yu JS, Hazen SL, Brown JM, Bayik D, Lathia J. Kay KE, et al. Among authors: brown jm. J Clin Invest. 2024 Nov 19:e177824. doi: 10.1172/JCI177824. Online ahead of print. J Clin Invest. 2024. PMID: 39561012 Free article.
NK2R control of energy expenditure and feeding to treat metabolic diseases.
Sass F, Ma T, Ekberg JH, Kirigiti M, Ureña MG, Dollet L, Brown JM, Basse AL, Yacawych WT, Burm HB, Andersen MK, Nielsen TS, Tomlinson AJ, Dmytiyeva O, Christensen DP, Bader L, Vo CT, Wang Y, Rausch DM, Kristensen CK, Gestal-Mato M, In Het Panhuis W, Sjøberg KA, Kernodle S, Petersen JE, Pavlovskyi A, Sandhu M, Moltke I, Jørgensen ME, Albrechtsen A, Grarup N, Babu MM, Rensen PCN, Kooijman S, Seeley RJ, Worthmann A, Heeren J, Pers TH, Hansen T, Gustafsson MBF, Tang-Christensen M, Kilpeläinen TO, Myers MG Jr, Kievit P, Schwartz TW, Hansen JB, Gerhart-Hines Z. Sass F, et al. Among authors: brown jm. Nature. 2024 Nov 13. doi: 10.1038/s41586-024-08207-0. Online ahead of print. Nature. 2024. PMID: 39537932
CREEPING FAT-DERIVED FREE FATTY ACIDS INDUCE HYPERPLASIA OF INTESTINAL MUSCULARIS PROPRIA MUSCLE CELLS - A NOVEL LINK BETWEEN FAT AND INTESTINAL STRICTURE FORMATION IN CROHN'S DISEASE.
Liu W, Mao R, Nga Le TH, West G, Varadharajan V, Banerjee R, Doyon G, Mukherjee P, Nguyen QT, Mulya A, Rennison JH, Gordon IO, Cruise M, Hu S, Czarnecki D, Plesec T, Chandra J, Banerjee S, Wang J, Massey WJ, Goren I, Lin SN, Kurada S, Cohen BL, Qazi T, Holubar SD, Lipman J, Kanters A, Gliniak CM, Scherer PE, Chen MH, Siegmund B, Ivanov AI, Fiocchi C, Van Wagoner DR, Brown JM, Rieder F. Liu W, et al. Among authors: brown jm. Gastroenterology. 2024 Nov 8:S0016-5085(24)05659-2. doi: 10.1053/j.gastro.2024.10.034. Online ahead of print. Gastroenterology. 2024. PMID: 39522890
Kinetics of imidazole propionate from orally delivered histidine in mice and humans.
Warmbrunn MV, Attaye I, Horak A, Banerjee R, Massey WJ, Varadharajan V, Rampanelli E, Hao Y, Dutta S, Nemet I, Aron-Wisnewsky J, Clément K, Koopen A, Wortelboer K, Bergh PO, Davids M, Mohamed N, Kemper EM, Hazen S, Groen AK, van Raalte DH, Herrema H, Backhed F, Brown JM, Nieuwdorp M. Warmbrunn MV, et al. Among authors: brown jm. NPJ Biofilms Microbiomes. 2024 Nov 4;10(1):118. doi: 10.1038/s41522-024-00592-8. NPJ Biofilms Microbiomes. 2024. PMID: 39496629 Free PMC article.
2,113 results