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In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy.
Bowman RL, Dunbar AJ, Mishra T, Xiao W, Waarts MR, Maestre IF, Eisman SE, Cai L, Mowla S, Shah N, Youn A, Bennett L, Fontenard S, Gounder S, Gandhi A, Bowman M, O'Connor K, Zaroogian Z, Sánchez-Vela P, Martinez Benitez AR, Werewski M, Park Y, Csete IS, Krishnan A, Lee D, Boorady N, Potts CR, Jenkins MT, Cai SF, Carroll MP, Meyer SE, Miles LA, Ferrell PB Jr, Trowbridge JJ, Levine RL. Bowman RL, et al. Among authors: trowbridge jj. Cancer Cell. 2024 Nov 11;42(11):1955-1969.e7. doi: 10.1016/j.ccell.2024.10.009. Cancer Cell. 2024. PMID: 39532065
Clonal hematopoiesis, aging and Alzheimer's disease.
Sánchez Vela P, Trowbridge JJ, Levine RL. Sánchez Vela P, et al. Among authors: trowbridge jj. Nat Med. 2023 Jul;29(7):1605-1606. doi: 10.1038/s41591-023-02406-4. Nat Med. 2023. PMID: 37402877 No abstract available.
Metformin reduces the clonal fitness of Dnmt3aR878H hematopoietic stem and progenitor cells by reversing their aberrant metabolic and epigenetic state.
Hosseini M, Voisin V, Chegini A, Varesi A, Cathelin S, Ayyathan DM, Liu ACH, Yang Y, Wang V, Maher A, Grignano E, Reisz JA, D'Alessandro A, Young K, Wu Y, Fiumara M, Ferrari S, Naldini L, Gaiti F, Pai S, Schimmer AD, Bader GD, Dick JE, Xie SZ, Trowbridge JJ, Chan SM. Hosseini M, et al. Among authors: trowbridge jj. Res Sq [Preprint]. 2024 Feb 6:rs.3.rs-3874821. doi: 10.21203/rs.3.rs-3874821/v1. Res Sq. 2024. PMID: 38405837 Free PMC article. Preprint.
Characterization of an Osmr Conditional Knockout Mouse Model.
Schwartz LS, Saxl RL, Stearns T, Trowbridge JJ. Schwartz LS, et al. Among authors: trowbridge jj. bioRxiv [Preprint]. 2023 Nov 1:2023.10.27.564474. doi: 10.1101/2023.10.27.564474. bioRxiv. 2023. PMID: 37961653 Free PMC article. Preprint.
42 results