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134 results

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Page 1
In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy.
Bowman RL, Dunbar AJ, Mishra T, Xiao W, Waarts MR, Maestre IF, Eisman SE, Cai L, Mowla S, Shah N, Youn A, Bennett L, Fontenard S, Gounder S, Gandhi A, Bowman M, O'Connor K, Zaroogian Z, Sánchez-Vela P, Martinez Benitez AR, Werewski M, Park Y, Csete IS, Krishnan A, Lee D, Boorady N, Potts CR, Jenkins MT, Cai SF, Carroll MP, Meyer SE, Miles LA, Ferrell PB Jr, Trowbridge JJ, Levine RL. Bowman RL, et al. Cancer Cell. 2024 Nov 11;42(11):1955-1969.e7. doi: 10.1016/j.ccell.2024.10.009. Cancer Cell. 2024. PMID: 39532065
Targetable treatment resistance in thyroid cancer with clonal hematopoiesis.
Tiedje V, Vela PS, Yang JL, Untch BR, Boucai L, Stonestrom AJ, Costa AB, Expósito SF, Srivastava A, Kerpelev M, Greenberg J, Wereski M, Kulick A, Chen K, Qin T, Im SY, Krishnan A, Martinez Benitez AR, Pluvinet R, Sahin M, Menghrajani K, Krishnamoorthy GP, de Stanchina E, Zehir A, Satija R, Knauf J, Bowman RL, Esteller M, Devlin S, Berger MF, Koche RP, Fagin JA, Levine RL. Tiedje V, et al. Among authors: bowman rl. bioRxiv [Preprint]. 2024 Oct 11:2024.10.10.617685. doi: 10.1101/2024.10.10.617685. bioRxiv. 2024. PMID: 39415999 Free PMC article. Preprint.
Cellular taxonomy of the preleukemic bone marrow niche of acute myeloid leukemia.
Goda C, Kulkarni R, Bustos Y, Li W, Rudich A, Balcioglu O, Chidester S, Urs AP, Karunasiri M, Al-Marrawi Y, Korn E, Kanna S, Garfinkle EAR, Shah N, Wooten A, Mundy-Bosse B, Sehgal L, Zhang B, Marcucci G, Mardis ER, Garzon R, Bowman RL, Viny AD, Miles LA, Miller KE, Dorrance AM. Goda C, et al. Among authors: bowman rl. Leukemia. 2024 Oct 2. doi: 10.1038/s41375-024-02415-3. Online ahead of print. Leukemia. 2024. PMID: 39358541
PTPN11 Mutation Clonal Hierarchy in Acute Myeloid Leukemia.
Fobare S, Sharpe C, Quinn K, Bryant K, Miles LA, Bowman RL, Cheney C, Furby C, Long M, Fyock K, Wronowski B, Lerma JR, Mullaney A, Mrózek K, Nicolet D, Sesterhenn T, Johnstone ME, Rai SN, Pasare C, Zimmermann N, Carroll AJ, Stone RM, Wang ES, Kolitz JE, Powell BL, Perentesis JP, Eisfeld AK, Hertlein E, Byrd JC. Fobare S, et al. Among authors: bowman rl. bioRxiv [Preprint]. 2024 Sep 20:2024.09.18.612239. doi: 10.1101/2024.09.18.612239. bioRxiv. 2024. PMID: 39345464 Free PMC article. Preprint.
CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype-specific Vulnerability in IDH2- and TET2-mutant Cells.
Waarts MR, Mowla S, Boileau M, Martinez Benitez AR, Sango J, Bagish M, Fernández-Maestre I, Shan Y, Eisman SE, Park YC, Wereski M, Csete I, O'Connor K, Romero-Vega AC, Miles LA, Xiao W, Wu X, Koche RP, Armstrong SA, Shih AH, Papapetrou EP, Butler JM, Cai SF, Bowman RL, Levine RL. Waarts MR, et al. Among authors: bowman rl. Cancer Discov. 2024 Oct 4;14(10):1860-1878. doi: 10.1158/2159-8290.CD-23-1092. Cancer Discov. 2024. PMID: 38819218
Mapping genotypes to chromatin accessibility profiles in single cells.
Izzo F, Myers RM, Ganesan S, Mekerishvili L, Kottapalli S, Prieto T, Eton EO, Botella T, Dunbar AJ, Bowman RL, Sotelo J, Potenski C, Mimitou EP, Stahl M, El Ghaity-Beckley S, Arandela J, Raviram R, Choi DC, Hoffman R, Chaligné R, Abdel-Wahab O, Smibert P, Ghobrial IM, Scandura JM, Marcellino B, Levine RL, Landau DA. Izzo F, et al. Among authors: bowman rl. Nature. 2024 May;629(8014):1149-1157. doi: 10.1038/s41586-024-07388-y. Epub 2024 May 8. Nature. 2024. PMID: 38720070
Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity.
Schwede M, Jahn K, Kuipers J, Miles LA, Bowman RL, Robinson T, Furudate K, Uryu H, Tanaka T, Sasaki Y, Ediriwickrema A, Benard B, Gentles AJ, Levine R, Beerenwinkel N, Takahashi K, Majeti R. Schwede M, et al. Among authors: bowman rl. Leukemia. 2024 Jul;38(7):1501-1510. doi: 10.1038/s41375-024-02211-z. Epub 2024 Mar 11. Leukemia. 2024. PMID: 38467769 Free PMC article.
134 results