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Base-editing corrects metabolic abnormalities in a humanized mouse model for glycogen storage disease type-Ia.
Arnaoutova I, Aratyn-Schaus Y, Zhang L, Packer MS, Chen HD, Lee C, Gautam S, Gregoire FM, Leboeuf D, Boule S, Fernandez TP, Huang V, Cheng LI, Lung G, Bannister B, Decker J, Leete T, Shuang LS, Bock C, Kothiyal P, Grayson P, Mok KW, Quinn JJ, Young L, Barrera L, Ciaramella G, Mansfield BC, Chou JY. Arnaoutova I, et al. Among authors: shuang ls. Nat Commun. 2024 Nov 10;15(1):9729. doi: 10.1038/s41467-024-54108-1. Nat Commun. 2024. PMID: 39523369 Free PMC article.
Cytosine base editing inhibits hepatitis B virus replication and reduces HBsAg expression in vitro and in vivo.
Smekalova EM, Martinez MG, Combe E, Kumar A, Dejene S, Leboeuf D, Chen CY, Dorkin JR, Shuang LS, Kieft S, Young L, Barrera LA, Packer MS, Ciaramella G, Testoni B, Gregoire F, Zoulim F. Smekalova EM, et al. Among authors: shuang ls. Mol Ther Nucleic Acids. 2023 Dec 27;35(1):102112. doi: 10.1016/j.omtn.2023.102112. eCollection 2024 Mar 12. Mol Ther Nucleic Acids. 2023. PMID: 38292874 Free PMC article.
Genotyping by Sequencing of 393 Sorghum bicolor BTx623 × IS3620C Recombinant Inbred Lines Improves Sensitivity and Resolution of QTL Detection.
Kong W, Kim C, Zhang D, Guo H, Tan X, Jin H, Zhou C, Shuang LS, Goff V, Sezen U, Pierce G, Compton R, Lemke C, Robertson J, Rainville L, Auckland S, Paterson AH. Kong W, et al. Among authors: shuang ls. G3 (Bethesda). 2018 Jul 31;8(8):2563-2572. doi: 10.1534/g3.118.200173. G3 (Bethesda). 2018. PMID: 29853656 Free PMC article.