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Genomic insights for personalised care in lung cancer and smoking cessation: motivating at-risk individuals toward evidence-based health practices.
Chen T, Pham G, Fox L, Adler N, Wang X, Zhang J, Byun J, Han Y, Saunders GRB, Liu D, Bray MJ, Ramsey AT, McKay J, Bierut LJ, Amos CI, Hung RJ, Lin X, Zhang H, Chen LS. Chen T, et al. Among authors: zhang j, zhang h. EBioMedicine. 2024 Nov 8;110:105441. doi: 10.1016/j.ebiom.2024.105441. Online ahead of print. EBioMedicine. 2024. PMID: 39520911 Free PMC article.
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers.
Zhang YD, Hurson AN, Zhang H, Choudhury PP, Easton DF, Milne RL, Simard J, Hall P, Michailidou K, Dennis J, Schmidt MK, Chang-Claude J, Gharahkhani P, Whiteman D, Campbell PT, Hoffmeister M, Jenkins M, Peters U, Hsu L, Gruber SB, Casey G, Schmit SL, O'Mara TA, Spurdle AB, Thompson DJ, Tomlinson I, De Vivo I, Landi MT, Law MH, Iles MM, Demenais F, Kumar R, MacGregor S, Bishop DT, Ward SV, Bondy ML, Houlston R, Wiencke JK, Melin B, Barnholtz-Sloan J, Kinnersley B, Wrensch MR, Amos CI, Hung RJ, Brennan P, McKay J, Caporaso NE, Berndt SI, Birmann BM, Camp NJ, Kraft P, Rothman N, Slager SL, Berchuck A, Pharoah PDP, Sellers TA, Gayther SA, Pearce CL, Goode EL, Schildkraut JM, Moysich KB, Amundadottir LT, Jacobs EJ, Klein AP, Petersen GM, Risch HA, Stolzenberg-Solomon RZ, Wolpin BM, Li D, Eeles RA, Haiman CA, Kote-Jarai Z, Schumacher FR, Al Olama AA, Purdue MP, Scelo G, Dalgaard MD, Greene MH, Grotmol T, Kanetsky PA, McGlynn KA, Nathanson KL, Turnbull C, Wiklund F; Breast Cancer Association Consortium (BCAC); Barrett’s and Esophageal Adenocarcinoma Consortium (BEACON); Colon Cancer Family Registry (CCFR); Transdisciplinary Studies of Genetic Variation in Colorectal Cancer (… See abstract for full author list ➔ Zhang YD, et al. Among authors: zhang h. Nat Commun. 2020 Jul 3;11(1):3353. doi: 10.1038/s41467-020-16483-3. Nat Commun. 2020. PMID: 32620889 Free PMC article.
A new method for multiancestry polygenic prediction improves performance across diverse populations.
Zhang H, Zhan J, Jin J, Zhang J, Lu W, Zhao R, Ahearn TU, Yu Z, O'Connell J, Jiang Y, Chen T, Okuhara D; 23andMe Research Team; Garcia-Closas M, Lin X, Koelsch BL, Chatterjee N. Zhang H, et al. Among authors: zhang j. Nat Genet. 2023 Oct;55(10):1757-1768. doi: 10.1038/s41588-023-01501-z. Epub 2023 Sep 25. Nat Genet. 2023. PMID: 37749244 Free PMC article.
An Ensemble Penalized Regression Method for Multi-ancestry Polygenic Risk Prediction.
Zhang J, Zhan J, Jin J, Ma C, Zhao R, O'Connell J, Jiang Y; 23andMe Research Team; Koelsch BL, Zhang H, Chatterjee N. Zhang J, et al. Among authors: zhang h. bioRxiv [Preprint]. 2024 Apr 10:2023.03.15.532652. doi: 10.1101/2023.03.15.532652. bioRxiv. 2024. Update in: Nat Commun. 2024 Apr 15;15(1):3238. doi: 10.1038/s41467-024-47357-7 PMID: 36993331 Free PMC article. Updated. Preprint.
Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers.
Blechter B, Wang X, Shi J, Shiraishi K, Choi J, Matsuo K, Chen TY, Dai J, Hung RJ, Chen K, Shu XO, Kim YT, Choudhury PP, Williams J, Landi MT, Lin D, Zheng W, Yin Z, Zhou B, Wang J, Seow WJ, Song L, Chang IS, Hu W, Chien LH, Cai Q, Hong YC, Kim HN, Wu YL, Wong MP, Richardson BD, Li S, Zhang T, Breeze C, Wang Z, Bassig BA, Kim JH, Albanes D, Wong JY, Shin MH, Chung LP, Yang Y, An SJ, Zheng H, Yatabe Y, Zhang XC, Kim YC, Caporaso NE, Chang J, Man Ho JC, Kubo M, Daigo Y, Song M, Momozawa Y, Kamatani Y, Kobayashi M, Okubo K, Honda T, Hosgood HD, Kunitoh H, Watanabe SI, Miyagi Y, Nakayama H, Matsumoto S, Horinouchi H, Tsuboi M, Hamamoto R, Goto K, Ohe Y, Takahashi A, Goto A, Minamiya Y, Hara M, Nishida Y, Takeuchi K, Wakai K, Matsuda K, Murakami Y, Shimizu K, Suzuki H, Saito M, Ohtaki Y, Tanaka K, Wu T, Wei F, Dai H, Machiela MJ, Su J, Kim YH, Oh IJ, Fun Lee VH, Chang GC, Tsai YH, Che KY, Huang MS, Su WC, Chen YM, Seow A, Park JY, Kweon SS, Chen KC, Gao YT, Qian B, Wu C, Lu D, Liu J, Schwartz AG, Houlston R, Spitz MR, Gorlov IP, Wu X, Yang P, Lam S, Tardon A, Chen C, Bojesen SE, Johansson M, Risch A, Bickeböller H, Ji BT, Wichmann HE, Christiani DC, Rennert G, Arnold S, B… See abstract for full author list ➔ Blechter B, et al. Among authors: zhang xc, zhang t, zhang h. medRxiv [Preprint]. 2024 Nov 6:2024.06.26.24309127. doi: 10.1101/2024.06.26.24309127. medRxiv. 2024. PMID: 38978671 Free PMC article. Preprint.
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