Elmenoufy AH - Search Results

1

The synergy between alkylating agents and ERCC1-XPF inhibitors is p53 dependent.

Ciniero G, Pedro TM, Dumontet C, Elmenoufy AH, West FG, Weinfeld M, Gentile F, Tuszynski JA, Cros-Perrial E, Jordheim LP. Ciniero G, et al. Among authors: elmenoufy ah. Fundam Clin Pharmacol. 2024 Nov 8. doi: 10.1111/fcp.13043. Online ahead of print. Fundam Clin Pharmacol. 2024. PMID: 39520092

2

Computer-aided drug design of small molecule inhibitors of the ERCC1-XPF protein-protein interaction.

Gentile F, Elmenoufy AH, Ciniero G, Jay D, Karimi-Busheri F, Barakat KH, Weinfeld M, West FG, Tuszynski JA. Gentile F, et al. Among authors: elmenoufy ah. Chem Biol Drug Des. 2020 Apr;95(4):460-471. doi: 10.1111/cbdd.13660. Epub 2020 Jan 20. Chem Biol Drug Des. 2020. PMID: 31891209

3

Design, synthesis and in vitro cell-free/cell-based biological evaluations of novel ERCC1-XPF inhibitors targeting DNA repair pathway.

Elmenoufy AH, Gentile F, Jay D, Karimi-Busheri F, Yang X, Soueidan OM, Mani RS, Ciniero G, Tuszynski JA, Weinfeld M, West FG. Elmenoufy AH, et al. Eur J Med Chem. 2020 Oct 15;204:112658. doi: 10.1016/j.ejmech.2020.112658. Epub 2020 Jul 22. Eur J Med Chem. 2020. PMID: 32738410

4

Enhancing the activity of platinum-based drugs by improved inhibitors of ERCC1-XPF-mediated DNA repair.

Ciniero G, Elmenoufy AH, Gentile F, Weinfeld M, Deriu MA, West FG, Tuszynski JA, Dumontet C, Cros-Perrial E, Jordheim LP. Ciniero G, et al. Among authors: elmenoufy ah. Cancer Chemother Pharmacol. 2021 Feb;87(2):259-267. doi: 10.1007/s00280-020-04213-x. Epub 2021 Jan 5. Cancer Chemother Pharmacol. 2021. PMID: 33399940

5

Targeting DNA Repair in Tumor Cells via Inhibition of ERCC1-XPF.

Elmenoufy AH, Gentile F, Jay D, Karimi-Busheri F, Yang X, Soueidan OM, Weilbeer C, Mani RS, Barakat KH, Tuszynski JA, Weinfeld M, West FG. Elmenoufy AH, et al. J Med Chem. 2019 Sep 12;62(17):7684-7696. doi: 10.1021/acs.jmedchem.9b00326. Epub 2019 Aug 22. J Med Chem. 2019. PMID: 31369707

6

Modulation of ERCC1-XPF Heterodimerization Inhibition via Structural Modification of Small Molecule Inhibitor Side-Chains.

Weilbeer C, Jay D, Donnelly JC, Gentile F, Karimi-Busheri F, Yang X, Mani RS, Yu Y, Elmenoufy AH, Barakat KH, Tuszynski JA, Weinfeld M, West FG. Weilbeer C, et al. Among authors: elmenoufy ah. Front Oncol. 2022 Mar 17;12:819172. doi: 10.3389/fonc.2022.819172. eCollection 2022. Front Oncol. 2022. PMID: 35372043 Free PMC article.

7

Nanocomposite-Based Photodynamic Therapy Strategies for Deep Tumor Treatment.

Hu J, Tang Y, Elmenoufy AH, Xu H, Cheng Z, Yang X. Hu J, et al. Among authors: elmenoufy ah. Small. 2015 Nov 25;11(44):5860-87. doi: 10.1002/smll.201501923. Epub 2015 Sep 23. Small. 2015. PMID: 26398119 Review.

8

A novel deep photodynamic therapy modality combined with CT imaging established via X-ray stimulated silica-modified lanthanide scintillating nanoparticles.

Elmenoufy AH, Tang Y, Hu J, Xu H, Yang X. Elmenoufy AH, et al. Chem Commun (Camb). 2015 Aug 7;51(61):12247-50. doi: 10.1039/c5cc04135j. Chem Commun (Camb). 2015. PMID: 26136105

9

Highly Efficient FRET System Capable of Deep Photodynamic Therapy Established on X-ray Excited Mesoporous LaF3:Tb Scintillating Nanoparticles.

Tang Y, Hu J, Elmenoufy AH, Yang X. Tang Y, et al. Among authors: elmenoufy ah. ACS Appl Mater Interfaces. 2015 Jun 10;7(22):12261-9. doi: 10.1021/acsami.5b03067. Epub 2015 May 26. ACS Appl Mater Interfaces. 2015. PMID: 25974980

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