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Page 1
Unsupervised Classification of the Host Response Identifies Dominant Pathobiological Signatures of Sepsis in Sub-Saharan Africa.
Cummings MJ, Lutwama JJ, Owor N, Tomoiaga AS, Ross JE, Muwanga M, Nsereko C, Nayiga I, Kyebambe S, Shinyale J, Ochar T, Kiwubeyi M, Nankwanga R, Nie K, Xie H, Miake-Lye S, Villagomez B, Qi J, Reynolds SJ, Nakibuuka MC, Lu X, Kayiwa J, Haumba M, Nakaseegu J, Che X, Wayengera M, Ghosh S, Kim-Schulze S, Lipkin WI, Bakamutumaho B, O'Donnell MR. Cummings MJ, et al. Among authors: tomoiaga as. Am J Respir Crit Care Med. 2024 Nov 8. doi: 10.1164/rccm.202407-1394OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 39514831
COVID-19 immune signatures in Uganda persist in HIV co-infection and diverge by pandemic phase.
Cummings MJ, Bakamutumaho B, Lutwama JJ, Owor N, Che X, Astorkia M, Postler TS, Kayiwa J, Kiconco J, Muwanga M, Nsereko C, Rwamutwe E, Nayiga I, Kyebambe S, Haumba M, Bosa HK, Ocom F, Watyaba B, Kikaire B, Tomoiaga AS, Kisaka S, Kiwanuka N, Lipkin WI, O'Donnell MR; Collaboration for Clinical and Laboratory Characterization of COVID-19 in Uganda. Cummings MJ, et al. Among authors: tomoiaga as. Nat Commun. 2024 Feb 17;15(1):1475. doi: 10.1038/s41467-024-45204-3. Nat Commun. 2024. PMID: 38368384 Free PMC article.
Broad genic repression domains signify enhanced silencing of oncogenes.
Zhao D, Zhang L, Zhang M, Xia B, Lv J, Gao X, Wang G, Meng Q, Yi Y, Zhu S, Tomoiaga AS, Lee MG, Cooke JP, Cao Q, Chen K. Zhao D, et al. Among authors: tomoiaga as. Nat Commun. 2020 Nov 3;11(1):5560. doi: 10.1038/s41467-020-18913-8. Nat Commun. 2020. PMID: 33144558 Free PMC article.
A Transcriptomic Classifier Model Identifies High-Risk Endotypes in a Prospective Study of Sepsis in Uganda.
Cummings MJ, Bakamutumaho B, Tomoiaga AS, Owor N, Jain K, Price A, Kayiwa J, Namulondo J, Byaruhanga T, Muwanga M, Nsereko C, Nayiga I, Kyebambe S, Sameroff S, Che X, Lutwama JJ, Lipkin WI, O'Donnell MR. Cummings MJ, et al. Among authors: tomoiaga as. Crit Care Med. 2024 Mar 1;52(3):475-482. doi: 10.1097/CCM.0000000000006023. Epub 2023 Aug 7. Crit Care Med. 2024. PMID: 37548511
Machine learning uncovers cell identity regulator by histone code.
Xia B, Zhao D, Wang G, Zhang M, Lv J, Tomoiaga AS, Li Y, Wang X, Meng S, Cooke JP, Cao Q, Zhang L, Chen K. Xia B, et al. Among authors: tomoiaga as. Nat Commun. 2020 Jun 1;11(1):2696. doi: 10.1038/s41467-020-16539-4. Nat Commun. 2020. PMID: 32483223 Free PMC article.