Sharaky M - Search Results

1

A study of the role of androgen receptor and androgen receptor variant 7 in TNBC patients and the effect of their targeting by Enzalutamide and EPI-001 in MDA-MB-231.

Ali BM, El-Abhar HS, Mohamed G, Nassar HR, Aliedin N, Sharaky M, Shouman SA, Kamel M. Ali BM, et al. Among authors: sharaky m. J Steroid Biochem Mol Biol. 2024 Nov 12;245:106636. doi: 10.1016/j.jsbmb.2024.106636. Online ahead of print. J Steroid Biochem Mol Biol. 2024. PMID: 39536950

2

Anticancer activity of EMD37 against human head and neck cancer: Impact on apoptotic and inflammatory machineries.

Sharaky M, Dokla EME, Abdel-Aziz AK. Sharaky M, et al. Toxicol In Vitro. 2024 Nov 5;102:105967. doi: 10.1016/j.tiv.2024.105967. Online ahead of print. Toxicol In Vitro. 2024. PMID: 39510359

3

Investigating the anti-inflammatory potential of N-amidic acid organoselenium candidates: biological assessments, molecular docking, and molecular dynamics simulations.

Althikrallah HA, Shaaban S, Elmaaty AA, Ba-Ghazal H, Almarri MN, Sharaky M, Alnajjar R, Al-Karmalawy AA. Althikrallah HA, et al. Among authors: sharaky m. RSC Adv. 2024 Oct 9;14(44):31990-32000. doi: 10.1039/d4ra04762a. eCollection 2024 Oct 9. RSC Adv. 2024. PMID: 39391620 Free PMC article.

4

Muti-target rationale design of novel substituted N-phenyl-2-((6-phenylpyridazin-3-yl)thio)acetamide candidates as telomerase/JAK1/STAT3/TLR4 inhibitors: In vitro and in vivo investigations.

Shaldam MA, Mousa MHA, Tawfik HO, El-Dessouki AM, Sharaky M, Saleh MM, Alzahrani AYA, Moussa SB, Al-Karmalawy AA. Shaldam MA, et al. Among authors: sharaky m. Bioorg Chem. 2024 Sep 24;153:107843. doi: 10.1016/j.bioorg.2024.107843. Online ahead of print. Bioorg Chem. 2024. PMID: 39332072

5

Design and synthesis of novel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators.

Abdel-Motaal M, Aldakhili DA, Farag AB, Elmaaty AA, Sharaky M, Mohamed NA, Shaaban S, Alzahrani AYA, Al-Karmalawy AA. Abdel-Motaal M, et al. Among authors: sharaky m. RSC Med Chem. 2024 Aug 30;15(11):3800-16. doi: 10.1039/d4md00585f. Online ahead of print. RSC Med Chem. 2024. PMID: 39290384 Free article.

6

Pyridazinone-based derivatives as anticancer agents endowed with anti-microbial activity: molecular design, synthesis, and biological investigation.

El-Nagar MKS, Shahin MI, El-Behairy MF, Taher ES, El-Badawy MF, Sharaky M, Abou El Ella DA, Abouzid KAM, Adel M. El-Nagar MKS, et al. Among authors: sharaky m. RSC Med Chem. 2024 Aug 16;15(10):3529-57. doi: 10.1039/d4md00481g. Online ahead of print. RSC Med Chem. 2024. PMID: 39246752 Free article.

7

2-methoxyestradiol sensitizes tamoxifen-resistant MCF-7 breast cancer cells via downregulating HIF-1α.

Attia YM, Mokhlis HA, Ismail A, Doghish AS, Sobhy MH, Hassanein SS, El-Dakroury WA, Mariee AD, Salama SA, Sharaky M. Attia YM, et al. Among authors: sharaky m. Med Oncol. 2024 Aug 21;41(9):232. doi: 10.1007/s12032-024-02471-w. Med Oncol. 2024. PMID: 39167288 Free PMC article.

8

Organoselenium-based Azomethines as Apoptosis Inducers in Colorectal Carcinoma via P53, BAX, Caspase-3, Caspase-6, and Caspase-9 Modulations.

Shaaban S, Hammouda MM, Althikrallah HA, Al Nawah JY, Ba-Ghazal H, Sharaky M, Abulkhair HS, Al-Karmalawy AA. Shaaban S, et al. Among authors: sharaky m. Curr Med Chem. 2024 Aug 12. doi: 10.2174/0109298673319340240809104237. Online ahead of print. Curr Med Chem. 2024. PMID: 39136522

9

Synthesis of novel piperazine-based bis(thiazole)(1,3,4-thiadiazole) hybrids as anti-cancer agents through caspase-dependent apoptosis.

Mohamed DM, Kheder NA, Sharaky M, Nafie MS, Dawood KM, Abbas AA. Mohamed DM, et al. Among authors: sharaky m. RSC Adv. 2024 Aug 9;14(34):24992-25006. doi: 10.1039/d4ra05091f. eCollection 2024 Aug 5. RSC Adv. 2024. PMID: 39131497 Free PMC article.

10

Design, synthesis and biological evaluation of novel pyrazole-based compounds as potential chemotherapeutic agents.

Jaballah MY, Elleboudy NS, Sharaky M, M Abouzid KA, Shahin MI. Jaballah MY, et al. Among authors: sharaky m. Future Med Chem. 2024 Jul 2;16(13):1299-1311. doi: 10.1080/17568919.2024.2347090. Epub 2024 May 20. Future Med Chem. 2024. PMID: 39109431

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