Arai K - Search Results

1

ER Oxidoreductin 1-Like Activity of Cyclic Diselenides Drives Protein Disulfide Isomerase in an Electron Relay System.

Mikami R, Nishizawa Y, Iwata Y, Kanemura S, Okumura M, Arai K. Mikami R, et al. Among authors: arai k. Chembiochem. 2024 Nov 6:e202400739. doi: 10.1002/cbic.202400739. Online ahead of print. Chembiochem. 2024. PMID: 39505703

2

Abnormal Enhancement of Protein Disulfide Isomerase-like Activity of a Cyclic Diselenide Conjugated with a Basic Amino Acid by Inserting a Glycine Spacer.

Mikami R, Tsukagoshi S, Arai K. Mikami R, et al. Among authors: arai k. Biology (Basel). 2021 Oct 24;10(11):1090. doi: 10.3390/biology10111090. Biology (Basel). 2021. PMID: 34827083 Free PMC article.

3

Basic Amino Acid Conjugates of 1,2-Diselenan-4-amine with Protein Disulfide Isomerase-like Functions as a Manipulator of Protein Quality Control.

Tsukagoshi S, Mikami R, Arai K. Tsukagoshi S, et al. Among authors: arai k. Chem Asian J. 2020 Sep 1;15(17):2646-2652. doi: 10.1002/asia.202000682. Epub 2020 Jul 29. Chem Asian J. 2020. PMID: 32662226

4

S-Denitrosylase-Like Activity of Cyclic Diselenides Conjugated with Xaa-His Dipeptide: Role of Proline Spacer as a Key Activity Booster.

Mikami R, Tsukagoshi S, Oda Y, Arai K. Mikami R, et al. Among authors: arai k. Chembiochem. 2022 Mar 4;23(5):e202100394. doi: 10.1002/cbic.202100394. Epub 2021 Sep 13. Chembiochem. 2022. PMID: 34350692

5

Semi-enzymatic acceleration of oxidative protein folding by N-methylated heteroaromatic thiols.

Okada S, Matsumoto Y, Takahashi R, Arai K, Kanemura S, Okumura M, Muraoka T. Okada S, et al. Among authors: arai k. Chem Sci. 2023 Jun 16;14(28):7630-7636. doi: 10.1039/d3sc01540h. eCollection 2023 Jul 19. Chem Sci. 2023. PMID: 37476727 Free PMC article.

6

Boosting the enzymatic activity of CxxC motif-containing PDI family members.

Kuramochi T, Yamashita Y, Arai K, Kanemura S, Muraoka T, Okumura M. Kuramochi T, et al. Among authors: arai k. Chem Commun (Camb). 2024 Jun 11;60(48):6134-6137. doi: 10.1039/d4cc01712a. Chem Commun (Camb). 2024. PMID: 38829522

7

Modeling Type-1 Iodothyronine Deiodinase with Peptide-Based Aliphatic Diselenides: Potential Role of Highly Conserved His and Cys Residues as a General Acid Catalyst.

Arai K, Toba H, Yamamoto N, Ito M, Mikami R. Arai K, et al. Chemistry. 2023 Jan 12;29(3):e202202387. doi: 10.1002/chem.202202387. Epub 2022 Nov 21. Chemistry. 2023. PMID: 36254793

8

Diselenide-bond replacement of the external disulfide bond of insulin increases its oligomerization leading to sustained activity.

Arai K, Okumura M, Lee YH, Katayama H, Mizutani K, Lin Y, Park SY, Sawada K, Toyoda M, Hojo H, Inaba K, Iwaoka M. Arai K, et al. Commun Chem. 2023 Nov 21;6(1):258. doi: 10.1038/s42004-023-01056-4. Commun Chem. 2023. PMID: 37989850 Free PMC article.

9

Protein Folding in the Presence of Water-Soluble Cyclic Diselenides with Novel Oxidoreductase and Isomerase Activities.

Arai K, Ueno H, Asano Y, Chakrabarty G, Shimodaira S, Mugesh G, Iwaoka M. Arai K, et al. Chembiochem. 2018 Feb 2;19(3):207-211. doi: 10.1002/cbic.201700624. Epub 2017 Dec 29. Chembiochem. 2018. PMID: 29197144

10

Preparation of Selenoinsulin as a Long-Lasting Insulin Analogue.

Arai K, Takei T, Okumura M, Watanabe S, Amagai Y, Asahina Y, Moroder L, Hojo H, Inaba K, Iwaoka M. Arai K, et al. Angew Chem Int Ed Engl. 2017 May 8;56(20):5522-5526. doi: 10.1002/anie.201701654. Epub 2017 Apr 10. Angew Chem Int Ed Engl. 2017. PMID: 28394477

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