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958 results

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Page 1
Machine learning-based clustering identifies obesity subgroups with differential multi-omics profiles and metabolic patterns.
Anwar MY, Highland H, Buchanan VL, Graff M, Young K, Taylor KD, Tracy RP, Durda P, Liu Y, Johnson CW, Aguet F, Ardlie KG, Gerszten RE, Clish CB, Lange LA, Ding J, Goodarzi MO, Chen YI, Peloso GM, Guo X, Stanislawski MA, Rotter JI, Rich SS, Justice AE, Liu CT, North K. Anwar MY, et al. Among authors: rich ss. Obesity (Silver Spring). 2024 Nov;32(11):2024-2034. doi: 10.1002/oby.24137. Obesity (Silver Spring). 2024. PMID: 39497627
Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans.
Goodarzi MO, Langefeld CD, Xiang AH, Chen YD, Guo X, Hanley AJ, Raffel LJ, Kandeel F, Nadler JL, Buchanan TA, Norris JM, Fingerlin TE, Lorenzo C, Rewers MJ, Haffner SM, Bowden DW, Rich SS, Bergman RN, Rotter JI, Watanabe RM, Wagenknecht LE. Goodarzi MO, et al. Among authors: rich ss. Obesity (Silver Spring). 2014 Apr;22(4):1157-64. doi: 10.1002/oby.20639. Obesity (Silver Spring). 2014. PMID: 24124113 Free PMC article.
New genetic loci link adipose and insulin biology to body fat distribution.
Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JMW, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C, Gustafsson S, Day FR, Esko T, Fall T, Kutalik Z, Luan J, Randall JC, Scherag A, Vedantam S, Wood AR, Chen J, Fehrmann R, Karjalainen J, Kahali B, Liu CT, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bragg-Gresham JL, Buyske S, Demirkan A, Ehret GB, Feitosa MF, Goel A, Jackson AU, Johnson T, Kleber ME, Kristiansson K, Mangino M, Leach IM, Medina-Gomez C, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Stančáková A, Sung YJ, Tanaka T, Teumer A, Van Vliet-Ostaptchouk JV, Yengo L, Zhang W, Albrecht E, Ärnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Böhringer S, Bonnet F, Böttcher Y, Bruinenberg M, Carba DB, Caspersen IH, Clarke R, Daw EW, Deelen J, Deelman E, Delgado G, Doney AS, Eklund N, Erdos MR, Estrada K, Eury E, Friedrich N, Garcia ME, Giedraitis V, Gigante B, Go AS, Golay A, Grallert H, Grammer TB, Gräßler J, Grewal J, Groves CJ, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heikkilä K, Herzig KH, Helmer Q, Hi… See abstract for full author list ➔ Shungin D, et al. Nature. 2015 Feb 12;518(7538):187-196. doi: 10.1038/nature14132. Nature. 2015. PMID: 25673412 Free PMC article.
Rationale, design and baseline characteristics of the Microbiome and Insulin Longitudinal Evaluation Study (MILES).
Jensen ET, Bertoni AG, Crago OL, Hoffman KL, Wood AC, Arzumanyan Z, Lam LK, Roll K, Sandow K, Wu M, Rich SS, Rotter JI, Chen YI, Petrosino JF, Goodarzi MO. Jensen ET, et al. Among authors: rich ss. Diabetes Obes Metab. 2020 Nov;22(11):1976-1984. doi: 10.1111/dom.14145. Epub 2020 Aug 20. Diabetes Obes Metab. 2020. PMID: 32687239 Free PMC article.
Associations between DNA methylation and BMI vary by metabolic health status: a potential link to disparate cardiovascular outcomes.
Do WL, Nguyen S, Yao J, Guo X, Whitsel EA, Demerath E, Rotter JI, Rich SS, Lange L, Ding J, Van Den Berg D, Liu Y, Justice AE, Guan W, Horvath S, Assimes TL, Bhatti P, Jordahl K, Shadyab A, Valencia CI, Stein AD, Smith A, Staimez LR, Conneely K, Narayan KMV. Do WL, et al. Among authors: rich ss. Clin Epigenetics. 2021 Dec 22;13(1):230. doi: 10.1186/s13148-021-01194-3. Clin Epigenetics. 2021. PMID: 34937574 Free PMC article.
Associations between adherence to the dietary approaches to stop hypertension (DASH) diet and six glucose homeostasis traits in the Microbiome and Insulin Longitudinal Evaluation Study (MILES).
Ramesh G, Wood AC, Allison MA, Rich SS, Jensen ET, Chen YI, Rotter JI, Bertoni AG, Goodarzi MO. Ramesh G, et al. Among authors: rich ss. Nutr Metab Cardiovasc Dis. 2022 Jun;32(6):1418-1426. doi: 10.1016/j.numecd.2022.03.014. Epub 2022 Mar 19. Nutr Metab Cardiovasc Dis. 2022. PMID: 35459606 Free PMC article.
Lymphocyte activation gene-3-associated protein networks are associated with HDL-cholesterol and mortality in the Trans-omics for Precision Medicine program.
Manichaikul A, Lin H, Kang C, Yang C, Rich SS, Taylor KD, Guo X, Rotter JI, Craig Johnson W, Cornell E, Tracy RP, Peter Durda J, Liu Y, Vasan RS, Adrienne Cupples L, Gerszten RE, Clish CB, Jain D, Conomos MP, Blackwell T, Papanicolaou GJ, Rodriguez A. Manichaikul A, et al. Among authors: rich ss. Commun Biol. 2022 May 2;5(1):362. doi: 10.1038/s42003-022-03304-0. Commun Biol. 2022. PMID: 35501457 Free PMC article.
Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals.
Tahir UA, Katz DH, Avila-Pachecho J, Bick AG, Pampana A, Robbins JM, Yu Z, Chen ZZ, Benson MD, Cruz DE, Ngo D, Deng S, Shi X, Zheng S, Eisman AS, Farrell L, Hall ME, Correa A, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Yao J, Chen YI, Manichaikul AW, Ruberg FL, Blaner WS, Jain D; NHLBI Trans-Omics for Precision Medicine 1 Consortium; Bouchard C, Sarzynski MA, Rich SS, Rotter JI, Wang TJ, Wilson JG, Clish CB, Natarajan P, Gerszten RE. Tahir UA, et al. Among authors: rich ss. Nat Commun. 2022 Aug 22;13(1):4923. doi: 10.1038/s41467-022-32275-3. Nat Commun. 2022. PMID: 35995766 Free PMC article.
Nontargeted and Targeted Metabolomic Profiling Reveals Novel Metabolite Biomarkers of Incident Diabetes in African Americans.
Chen ZZ, Pacheco JA, Gao Y, Deng S, Peterson B, Shi X, Zheng S, Tahir UA, Katz DH, Cruz DE, Ngo D, Benson MD, Robbins JM, Guo X, Del Rocio Sevilla Gonzalez M, Manning A, Correa A, Meigs JB, Taylor KD, Rich SS, Goodarzi MO, Rotter JI, Wilson JG, Clish CB, Gerszten RE. Chen ZZ, et al. Among authors: rich ss. Diabetes. 2022 Nov 1;71(11):2426-2437. doi: 10.2337/db22-0033. Diabetes. 2022. PMID: 35998269 Free PMC article.
Differences in Metabolomic Profiles Between Black and White Women and Risk of Coronary Heart Disease: an Observational Study of Women From Four US Cohorts.
Hu J, Yao J, Deng S, Balasubramanian R, Jiménez MC, Li J, Guo X, Cruz DE, Gao Y, Huang T, Zeleznik OA, Ngo D, Liu S, Rosal MC, Nassir R, Paynter NP, Albert CM, Tracy RP, Durda P, Liu Y, Taylor KD, Johnson WC, Sun Q, Rimm EB, Eliassen AH, Rich SS, Rotter JI, Gerszten RE, Clish CB, Rexrode KM. Hu J, et al. Among authors: rich ss. Circ Res. 2022 Sep 16;131(7):601-615. doi: 10.1161/CIRCRESAHA.121.320134. Epub 2022 Sep 2. Circ Res. 2022. PMID: 36052690 Free PMC article.
958 results