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Page 1
Serine and glycine physiology reversibly modulate retinal and peripheral nerve function.
Lim EW, Fallon RJ, Bates C, Ideguchi Y, Nagasaki T, Handzlik MK, Joulia E, Bonelli R, Green CR, Ansell BRE, Kitano M, Polis I, Roberts AJ, Furuya S, Allikmets R, Wallace M, Friedlander M, Metallo CM, Gantner ML. Lim EW, et al. Among authors: metallo cm. Cell Metab. 2024 Oct 1;36(10):2315-2328.e6. doi: 10.1016/j.cmet.2024.07.021. Epub 2024 Aug 26. Cell Metab. 2024. PMID: 39191258 Free article.
iPSC-derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function.
Eade KT, Ansell BRE, Giles S, Fallon R, Harkins-Perry S, Nagasaki T, Tzaridis S, Wallace M, Mills EA, Farashi S, Johnson A, Sauer L, Hart B, Diaz-Rubio ME, Bahlo M, Metallo C, Allikmets R, Gantner ML, Bernstein PS, Friedlander M. Eade KT, et al. J Clin Invest. 2023 May 1;133(9):e163771. doi: 10.1172/JCI163771. J Clin Invest. 2023. PMID: 37115691 Free PMC article.
Bempedoic acid suppresses diet-induced hepatic steatosis independently of ATP-citrate lyase.
Liu JY, Kuna RS, Pinheiro LV, Nguyen PTT, Welles JE, Drummond JM, Murali N, Sharma PV, Supplee JG, Shiue M, Zhao S, Farria AT, Kumar A, Ruchhoeft ML, Demetriadou C, Kantner DS, Chatoff A, Megill E, Titchenell PM, Snyder NW, Metallo CM, Wellen KE. Liu JY, et al. Among authors: metallo cm. Cell Metab. 2024 Oct 28:S1550-4131(24)00410-8. doi: 10.1016/j.cmet.2024.10.014. Online ahead of print. Cell Metab. 2024. PMID: 39471816
Sources and Sinks of Serine in Nutrition, Health, and Disease.
Handzlik MK, Metallo CM. Handzlik MK, et al. Among authors: metallo cm. Annu Rev Nutr. 2023 Aug 21;43:123-151. doi: 10.1146/annurev-nutr-061021-022648. Epub 2023 Jun 12. Annu Rev Nutr. 2023. PMID: 37307855 Free PMC article. Review.
Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia.
Laurila PP, Wohlwend M, Imamura de Lima T, Luan P, Herzig S, Zanou N, Crisol B, Bou-Sleiman M, Porcu E, Gallart-Ayala H, Handzlik MK, Wang Q, Jain S, D'Amico D, Salonen M, Metallo CM, Kutalik Z, Eichmann TO, Place N, Ivanisevic J, Lahti J, Eriksson JG, Auwerx J. Laurila PP, et al. Among authors: metallo cm. Nat Aging. 2022 Dec;2(12):1159-1175. doi: 10.1038/s43587-022-00309-6. Epub 2022 Dec 16. Nat Aging. 2022. PMID: 37118545
127 results