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Regulated Proteolysis Induces Aberrant Phase Transition of Biomolecular Condensates into Aggregates: A Protective Role for the Chaperone Clusterin.
Kamps J, Yuste-Checa P, Mamashli F, Schmitz M, Herrera MG, da Silva Correia SM, Gogte K, Bader V, Zerr I, Hartl FU, Bracher A, Winklhofer KF, Tatzelt J. Kamps J, et al. Among authors: schmitz m. J Mol Biol. 2024 Oct 28;436(23):168839. doi: 10.1016/j.jmb.2024.168839. Online ahead of print. J Mol Biol. 2024. PMID: 39476948 Free article.
Progress in CSF biomarker discovery in sCJD.
Llorens F, Schmitz M, Zerr I. Llorens F, et al. Among authors: schmitz m. Oncotarget. 2017 Jan 24;8(4):5666-5667. doi: 10.18632/oncotarget.13998. Oncotarget. 2017. PMID: 28086207 Free PMC article. No abstract available.
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies.
Linsenmeier L, Mohammadi B, Shafiq M, Frontzek K, Bär J, Shrivastava AN, Damme M, Song F, Schwarz A, Da Vela S, Massignan T, Jung S, Correia A, Schmitz M, Puig B, Hornemann S, Zerr I, Tatzelt J, Biasini E, Saftig P, Schweizer M, Svergun D, Amin L, Mazzola F, Varani L, Thapa S, Gilch S, Schätzl H, Harris DA, Triller A, Mikhaylova M, Aguzzi A, Altmeppen HC, Glatzel M. Linsenmeier L, et al. Among authors: schmitz m. Sci Adv. 2021 Nov 26;7(48):eabj1826. doi: 10.1126/sciadv.abj1826. Epub 2021 Nov 24. Sci Adv. 2021. PMID: 34818048 Free PMC article.
1,452 results